Evidence map›Paper›PMID 27028025›Full record

Observational studyDiabetic medicine : a journal of the British Diabetic Association2016

Glycaemic control and risk of incident urinary incontinence in women with Type 1 diabetes: results from the Diabetes Control and Complications Trial and Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) study.

S M Lenherr, J Q Clemens, B H Braffett, R L Dunn, P A Cleary, C Kim, W H Herman, J M Hotaling, A M Jacobson, J S Brown and 3 more

Open access · bronzeAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Diabetic medicine : a journal of the British Diabetic Association, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Article
  3. Urologic complications in diabetes.Journal of diabetes and its complications · 2022
    Review
  4. Review
  5. Article
  6. Autonomic neuropathy and urologic complications in diabetes.Autonomic neuroscience : basic & clinical · 2020
    Review
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 1 country.

S M LenherrDepartment of Urology, University of Michigan, Ann Arbor, MI, USA.
J Q ClemensDepartment of Urology, University of Michigan, Ann Arbor, MI, USA.
B H BraffettBiostatistics Center, George Washington University, Rockville, MD, USA.
R L DunnDepartment of Urology, University of Michigan, Ann Arbor, MI, USA.
P A ClearyBiostatistics Center, George Washington University, Rockville, MD, USA.
C KimDepartment of Medicine, University of Michigan, Ann Arbor, MI, USA.
W H HermanDepartment of Medicine, University of Michigan, Ann Arbor, MI, USA.
J M HotalingDepartment of Surgery, Division of Urology, University of Utah, Salt Lake City, UT, USA.
A M JacobsonWinthrop University Hospital, Research Institute, Mineola, NY, USA.
J S BrownDepartment of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco, CA, USA.
H WessellsDepartment of Urology, University of Washington School of Medicine and Harborview Medical Center, Seattle, WA, USA.
A V SarmaDepartment of Urology, University of Michigan, Ann Arbor, MI, USA. asarma@umich.edu.
DCCT/EDIC Research Group
University of Michigan–Ann Arbor · USGeorge Washington University · USUniversity of Utah · USUniversity of California, San Francisco · USUniversity of Washington · USWinthrop-University Hospital · US

Funding

Limited Competition for the Continuation of Epidemiology of Diabetes Interventions and Complications (EDIC) Study Clinical Research Center (Collaborative U01)U01DK094157 · NIDDK · CASE WESTERN RESERVE UNIVERSITY · PI Ionut Bebu, Barbara Halina Braffett · 2011 to 2026
$97.6M
Epidemiology of Diabetes Interventions and Complications Data Coordinating CenterU01DK094176 · NIDDK · GEORGE WASHINGTON UNIVERSITY · PI BEBU, IONUT, BRAFFETT, BARBARA HALINA · 2012 to 2022
$30.8M
Pilot and Feasibility (P and F) ProgramP30DK089503 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Kanakadurga Singer · 2010 to 2026
$20.3M
Uro Translational Research and Clinical Research Training (UroTRACT)T32DK007782 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI WEI, JOHN T · 2000 to 2019
$2.9M
Uro-EDICII: Risk and Progression of Urologic Complications in Type 1- DiabetesR01DK083927 · NIDDK · UNIVERSITY OF WASHINGTON · PI SARMA, ARUNA V, WESSELLS, HUNTER · 2009 to 2013
$2.7M
NIDDK NIH HHS P30 DK089503NIDDK NIH HHS R01 DK083927NIDDK NIH HHS T32 DK007782NIDDK NIH HHS U01 DK094157NIDDK NIH HHS U01 DK094176
6 · The paper itself

Abstract

aimsTo study the impact of glycaemic control on urinary incontinence in women who participated in the Diabetes Control and Complications Trial (DCCT; 1983-1993) and its observational follow-up study, the Epidemiology of Diabetes Interventions and Complications (EDIC; 1994-present).

methodsStudy participants were women who completed, at both years 10 (2003) and 17 (2010) of the EDIC follow-up, the urological assessment questionnaire (UroEDIC). Urinary incontinence was defined as self-reported involuntary leakage of urine that occurred at least weekly. Incident urinary incontinence was defined as weekly urinary incontinence present at EDIC year 17 but not at EDIC year 10. Multivariable regression models were used to examine the association of incident urinary incontinence with comorbid prevalent conditions and glycaemic control (mean HbA

resultsA total of 64 (15.3%) women with Type 1 diabetes (mean age 43.6 ± 6.3 years at EDIC year 10) reported incident urinary incontinence at EDIC year 17. When adjusted for clinical covariates (including age, DCCT cohort assignment, DCCT treatment arm, BMI, insulin dosage, parity, hysterectomy, autonomic neuropathy and urinary tract infection in the last year), the mean EDIC HbA

conclusionsIncident urinary incontinence was associated with higher HbA

Indexed as

AdolescentAdultBlood GlucoseDiabetes Mellitus, Type 1FemaleFollow-Up StudiesGlycated HemoglobinHumansIncidenceMiddle AgedMulticenter Studies as TopicRandomized Controlled Trials as TopicRisk FactorsSurveys and QuestionnairesUrinary IncontinenceYoung AdultBlood GlucoseGlycated Hemoglobin

Identifiers

PMID27028025
PMCPMC5045319
OpenAlexW2332534462

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.