Evidence map›Paper›PMID 27027891›Full record

Trial reportFunctional neurology

Effects of treadmill training on cognitive and motor features of patients with mild to moderate Parkinson's disease: a pilot, single-blind, randomized controlled trial.

Alessandro Picelli, Valentina Varalta, Camilla Melotti, Vanja Zatezalo, Cristina Fonte, Stefania Amato, Leopold Saltuari, Andrea Santamato, Pietro Fiore, Nicola Smania

Registry-linked trialOpen access · bronzeAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Functional neurology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04012086 (Intensive Physical Therapy Mitigates Cognitive Decline in People With Parkinson's Disease), which is not on this map. Cited by 39 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 11 pooled it
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04012086 nacompletednot on this map

Intensive Physical Therapy Mitigates Cognitive Decline in People With Parkinson's Disease

TypeinterventionalSponsorIRCCS National Neurological Institute "C. Mondino" FoundationRan2015 to 2018Enrolled40ConditionsParkinson Disease, Cognitive ImpairmentArmsPhysical therapy
3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 11 syntheses or guidelines pooled it, 91 citations in OpenAlex.

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  20. The role of exercise in Parkinson's Disease.Neurosciences (Riyadh, Saudi Arabia) · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Alessandro Picelli
Valentina Varalta
Camilla Melotti
Vanja Zatezalo
Cristina Fonte
Stefania Amato
Leopold Saltuari
Andrea Santamato
Pietro Fiore
Nicola Smania
University of Verona · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this pilot randomized controlled trial was to evaluate the effects of treadmill training on cognitive and motor performance in patients with Parkinson's disease (PD). Seventeen persons with mild to moderate PD were enrolled. Nine patients were allocated to the Intervention group and received twelve 45-minute sessions of treadmill training: one session a day, three days a week, for four consecutive weeks. Eight patients were allocated to the Control group; these patients did not undergo physical training but were required to have regular social interactions, following a specific lifestyle program. All the patients were evaluated at baseline and one month later. The primary outcome measures were the Frontal Assessment Battery-Italian version (FAB-it) and the 6-minute walking test (6MWT). At the one month evaluation significant differences were found between the groups in their performance on the FAB-it (p=0.005) and the 6MWT (p=0.018). Our findings support the hypothesis that treadmill training might effectively improve cognitive and motor features in patients with PD.

Indexed as

AgedCognitionExercise TestExercise TherapyFemaleHumansInterpersonal RelationsMaleMiddle AgedNeuropsychological TestsParkinson DiseasePilot ProjectsSeverity of Illness IndexSingle-Blind MethodTreatment OutcomeWalking

Identifiers

PMID27027891
PMCPMC4819815
OpenAlexW2469310836

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.