Trial reportVaccine2016
SMS text message reminders to improve infant vaccination coverage in Guatemala: A pilot randomized controlled trial.
Trial report in Vaccine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01663636 (SMS Mobile Technology for Vaccine Coverage and Acceptance in Guatemalan Infants), which is not on this map. Cited by 65 papers, 11 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
SMS Mobile Technology for Vaccine Coverage and Acceptance in Guatemalan Infants
Who cites it
65 citing papers in PubMed, 11 syntheses or guidelines pooled it, 132 citations in OpenAlex.
- Effectiveness of Catch-Up Vaccination Interventions Versus Standard or Usual Care Procedures in Increasing Adherence to Recommended Vaccinations Among Different Age Groups: Systematic Review and Meta-Analysis of Randomized Controlled Trials and Before-After Studies.JMIR public health and surveillance · 2024Pooled it
- SMS-based interventions for improving child and adolescent vaccine coverage and timeliness: a systematic review.BMC public health · 2024Pooled it
- Interventions for improving coverage of childhood immunisation in low- and middle-income countries.The Cochrane database of systematic reviews · 2023Pooled it
- Behavioral interventions for vaccination uptake: A systematic review and meta-analysis.Health policy (Amsterdam, Netherlands) · 2023Pooled it
- Short message service (SMS) reminders for childhood immunisation in low-income and middle-income countries: a systematic review and meta-analysis.BMJ global health · 2021Pooled it
- Targeted client communication via mobile devices for improving maternal, neonatal, and child health.The Cochrane database of systematic reviews · 2020Pooled it
- Effect of mobile text message reminders on routine childhood vaccination: a systematic review and meta-analysis.Systematic reviews · 2019Pooled it
- Patient reminder and recall interventions to improve immunization rates.The Cochrane database of systematic reviews · 2018Pooled it
- Immunization, urbanization and slums - a systematic review of factors and interventions.BMC public health · 2017Pooled it
- Mobile Health Interventions for Improving Health Outcomes in Youth: A Meta-analysis.JAMA pediatrics · 2017Pooled it
- Interventions for improving coverage of childhood immunisation in low- and middle-income countries.The Cochrane database of systematic reviews · 2016Pooled it
- The effect of mHealth application on improving childhood immunization coverage and timeliness: a case of the Gurage Zone, SNNPR, Ethiopia, a randomized controlled trial.BMC public health · 2025Trial
- SEARCH Study: Text Messages and Automated Phone Reminders for HPV Vaccination in Uganda: Randomized Controlled Trial.JMIR mHealth and uHealth · 2025Trial
- Effect of Mobile Phone Text Message Reminders on the Completion and Timely Receipt of Routine Childhood Vaccinations: Superiority Randomized Controlled Trial in Northwest Ethiopia.JMIR mHealth and uHealth · 2021Trial
- Impact of mobile phone delivered reminders and unconditional incentives on measles-containing vaccine timeliness and coverage: a randomised controlled trial in western Kenya.BMJ global health · 2021Trial
- Text message reminders to improve infant immunization in Guatemala: A randomized clinical trial.Vaccine · 2019Trial
- Mobile Phone Incentives for Childhood Immunizations in Rural India.Pediatrics · 2018Trial
- Trial
- Article
- Promoting Family Engagement With Early Childhood Developmental Screening via the Baby Steps Text Messaging and Web Portal System: Longitudinal Randomized Controlled Trial.JMIR pediatrics and parenting · 2025Article
5 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPatient reminder systems are an evidence-based way to improve childhood vaccination rates but are difficult to implement in low- and middle-income countries (LMICs). Short Message Service (SMS) texts may offer a potential low-cost solution, especially in LMICs where mobile phones are becoming more ubiquitous.
objectiveTo determine if an SMS-based vaccination reminder system aimed at improving completion of the infant primary immunization series is feasible and acceptable in Guatemala.
methodsA pilot randomized controlled trial was conducted at two public health clinics in Guatemala City. Infants aged 8-14 weeks presenting for the first dose of the primary immunization series were enrolled in March-April 2013. Participants randomized into the intervention received three SMS reminders one week before the second and third dose. A follow-up acceptability survey was administered to both groups.
resultsThe participation rate was 86.8% (321/370); 8 did not own a cell phone and 12 could not use SMS. 96.9% of intervention parents were sent at least one SMS reminder prior to visit 2 and 96.3% prior to visit 3. Both intervention and usual care participants had high rates of vaccine and visit completion, with a non-statistically significant higher percentage of children in the intervention completing both visit 2 (95.0% vs. 90.1%, p=.12) and visit 3 (84.4% vs. 80.7%, p=.69). More intervention vs. usual care parents agreed that SMS reminders would be helpful for remembering appointments (p<.0001), agreed to being interested in receiving future SMS reminders (p<.0001), and said that they would be willing to pay for future SMS reminders (p=.01).
conclusionThis proof of concept evaluation showed that a new application of SMS technology is feasible to implement in a LMIC with high user satisfaction. Larger studies with modifications in the SMS system are needed to determine effectiveness (Clinical Trial Registry NCT01663636).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.