Evidence map›Paper›PMID 27025746›Full record

ArticleAntibiotics (Basel, Switzerland)2014

Understanding Antibiotic Use in Minya District, Egypt: Physician and Pharmacist Prescribing and the Factors Influencing Their Practices.

Kathleen L Dooling, Amr Kandeel, Lauri A Hicks, Waleed El-Shoubary, Khaled Fawzi, Yasser Kandeel, Ahmad Etman, Anna Leena Lohiniva, Maha Talaat

Registry-linked trialAbstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04127682 (Antibiotic Prescription for Children With Acute Upper Respiratory Tract Infections in Assiut District), which is not on this map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04127682 completednot on this mapstarted 2021, after this paper: background citation

Antibiotic Prescription for Children With Acute Upper Respiratory Tract Infections in Assiut District: An Exploratory Study.

TypeobservationalSponsorAssiut UniversityRan2021 to 2022Enrolled186ConditionsAntibiotic Side EffectArmsAntibiotic KAP questionnaire
3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Pattern of antibiotic use among children caregivers: a cross-sectional study.The Journal of the Egyptian Public Health Association · 2024
    Article
  10. Article
  11. Article
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  13. Article
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  15. Multidrug-ResistantAntibiotics (Basel, Switzerland) · 2023
    Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Antibiotic resistance: still a cause of concern?OTA international : the open access journal of orthopaedic trauma · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kathleen L DoolingCenters of Disease Control and Prevention, Atlanta, GA 30333, USA. kathleen.dooling@peelregion.ca.
Amr KandeelMinistry of Health and Population, Cairo 11516, Egypt. kandeelamr@yahoo.com.
Lauri A HicksCenters of Disease Control and Prevention, Atlanta, GA 30333, USA. auq3@cdc.gov.
Waleed El-ShoubaryNaval Medical Research Unit, N3, Cairo 11517, Egypt. waleed.el-shoubary.eg@med.navy.mil.
Khaled FawziMinistry of Health and Population, Cairo 11516, Egypt. kfawzy56@yahoo.com.
Yasser KandeelMinistry of Health and Population, Cairo 11516, Egypt. ykandeel@hotmail.com.
Ahmad EtmanMinistry of Health and Population, Cairo 11516, Egypt. ahmed.hetman@hotmail.com.
Anna Leena LohinivaNaval Medical Research Unit, N3, Cairo 11517, Egypt. anna.leena.lohiniva@hotmail.com.
Maha TalaatNaval Medical Research Unit, N3, Cairo 11517, Egypt. maha.talaat.ctr.eg@med.navy.mil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Overuse of antibiotics has contributed to the emergence of antibiotic-resistant bacteria globally. In Egypt, patients can purchase antibiotics without a prescription, and we hypothesized frequent inappropriate antibiotic prescribing and dispensing. We interviewed physicians (n = 236) and pharmacists (n = 483) and conducted focus groups in Minya, Egypt, to assess attitudes and practices regarding antibiotic prescribing for outpatient acute respiratory infections (ARI). Antibiotics were reportedly prescribed most of the time or sometimes for colds by 150 (64%) physicians and 326 (81%) pharmacists. The most commonly prescribed antibiotics were β-lactams. Macrolides were the second most commonly prescribed for colds and sinusitis. The prescription of more than one antibiotic to treat pneumonia was reported by 85% of physicians. Most respondents thought antibiotic overuse contributes to resistance and reported "patient self-medication" as the biggest driver of overuse. Fifty physicians (21%) reported that they had prescribed antibiotics unnecessarily, citing patient over-the-counter access as the reason. Physicians <40 years of age and those who treat adults were more likely to prescribe antibiotics for colds. Overall, we found a high rate of unwarranted outpatient antibiotic prescribing and dispensing for ARIs. Patient access to OTC antibiotics contributes to over-prescribing. National guidelines for ARI treatment, provider education and national policy requiring a physician's prescription for antibiotics may improve appropriate antibiotic use in Egypt.

Indexed as

acute respiratory infectionantibiotic resistanceantibioticsbronchitiscoldEgyptpharmacistpneumoniasinusitis

Identifiers

PMID27025746
PMCPMC4790392

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.