Evidence map›Paper›PMID 27025743›Full record

ReviewAntibiotics (Basel, Switzerland)2014

Antimicrobial Stewardship and Urinary Tract Infections.

Lilian M Abbo, Thomas M Hooton

Registry-linked trialAbstract readReview
In one paragraph

Review in Antibiotics (Basel, Switzerland), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06387329 (Urinary Tract Infection Prophylaxis In Intradetrusor OnabotulinumtoxinA Procedures), which is not on this map. Cited by 63 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06387329 phase4recruitingnot on this mapstarted 2024, after this paper: background citation

Urinary Tract Infection Prophylaxis In Intradetrusor OnabotulinumtoxinA Procedures: A Randomized Controlled Trial

TypeinterventionalSponsorWalter Reed National Military Medical CenterRan2024 to 2025Enrolled100ConditionsOveractive Bladder, Bladder Pain SyndromeArmsNitrofurantoin 100 MG
3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Implementing an Antibiotic Stewardship Program: Guidelines by the Infectious Diseases Society of America and the Society for Healthcare Epidemiology of America.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2016
    Guideline
  3. Safety and immunogenicity of an adjuvantedHuman vaccines & immunotherapeutics · 2021
    Trial
  4. Article
  5. Article
  6. Observational
  7. Article
  8. Review
  9. Article
  10. The impact of Boric Acid tubes on quantitative urinary bacterial cultures in hospitalized patients.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2024
    Article
  11. Observational
  12. Article
  13. Potential of an Isolated Bacteriophage to InactivateAntibiotics (Basel, Switzerland) · 2024
    Article
  14. Article
  15. Article
  16. Dominance ofMicrobial genomics · 2023
    Article
  17. Article
  18. Article
  19. Article
  20. Review

3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Lilian M AbboDepartment of Medicine, Division of Infectious Diseases, University of Miami Miller School of Medicine, 1120 NW 14th Street, Suite 851, Miami, FL 33136, USA. labbo@med.miami.edu.
Thomas M HootonDepartment of Medicine, Division of Infectious Diseases, University of Miami Miller School of Medicine, 1120 NW 14th Street, Suite 851, Miami, FL 33136, USA. THooton@med.miami.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Urinary tract infections are the most common bacterial infections encountered in ambulatory and long-term care settings in the United States. Urine samples are the largest single category of specimens received by most microbiology laboratories and many such cultures are collected from patients who have no or questionable urinary symptoms. Unfortunately, antimicrobials are often prescribed inappropriately in such patients. Antimicrobial use, whether appropriate or inappropriate, is associated with the selection for antimicrobial-resistant organisms colonizing or infecting the urinary tract. Infections caused by antimicrobial-resistant organisms are associated with higher rates of treatment failures, prolonged hospitalizations, increased costs and mortality. Antimicrobial stewardship consists of avoidance of antimicrobials when appropriate and, when antimicrobials are indicated, use of strategies to optimize the selection, dosing, route of administration, duration and timing of antimicrobial therapy to maximize clinical cure while limiting the unintended consequences of antimicrobial use, including toxicity and selection of resistant microorganisms. This article reviews successful antimicrobial stewardship strategies in the diagnosis and treatment of urinary tract infections.

Indexed as

antibioticsantimicrobial resistanceantimicrobial stewardshipappropriatedurationurinary tract infectionsUTI

Identifiers

PMID27025743
PMCPMC4790395

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.