Evidence map›Paper›PMID 27025621›Full record

ReviewAntibiotics (Basel, Switzerland)2015

The Antimicrobial Stewardship Approach to Combating Clostridium Difficile.

Eric Wenzler, Surafel G Mulugeta, Larry H Danziger

Abstract readReview
In one paragraph

Review in Antibiotics (Basel, Switzerland), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Colonic epithelial regeneration shapes susceptibility tobioRxiv : the preprint server for biology · 2026
    Article
  2. Article
  3. Review
  4. Review
  5. A novel approach to correcting attribution ofAntimicrobial stewardship & healthcare epidemiology : ASHE · 2023
    Article
  6. Article
  7. Risk Factors for Hospital Readmission forPathogens (Basel, Switzerland) · 2022
    Article
  8. Article
  9. Article
  10. Article
  11. Understanding Clostridium difficile Colonization.Clinical microbiology reviews · 2018
    Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Eric WenzlerCollege of Pharmacy, University of Illinois at Chicago, Chicago, IL 60612, USA. wenzler@uic.edu.
Surafel G MulugetaCollege of Pharmacy, University of Illinois at Chicago, Chicago, IL 60612, USA. smulug2@uic.edu.
Larry H DanzigerCollege of Pharmacy, University of Illinois at Chicago, Chicago, IL 60612, USA. danziger@uic.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Clostridium difficile remains a major public health threat and continues to contribute to excess morbidity, mortality and healthcare costs. Antimicrobial stewardship programs have demonstrated success in combating C. difficile, primarily through antibiotic restrictive strategies. As the incidence and prevalence of C. difficile associate disease continues to increase both in the hospital and community setting, additional stewardship approaches are needed. This manuscript reviews stewardship interventions that have been successful against C. difficile associated disease and proposes future tactics that antimicrobial stewardship programs may employ to develop a more global approach to combat this difficult pathogen.

Indexed as

antimicrobial stewardshipClostridium difficilediarrheainfection controlrapid diagnosticsrestrictiontreatment

Identifiers

PMID27025621
PMCPMC4790327

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.