Evidence map›Paper›PMID 27025521›Full record

ArticleAntibiotics (Basel, Switzerland)2016

Controversies in Antimicrobial Stewardship: Focus on New Rapid Diagnostic Technologies and Antimicrobials.

Eric Wenzler, Jordan R Wong, Debra A Goff, Christopher A Jankowski, Karri A Bauer

Abstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Article
  3. Treatment-Resistant Bacterial Keratitis: Challenges and Solutions.Clinical ophthalmology (Auckland, N.Z.) · 2020
    Review
  4. Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Diagnosing sepsis - The role of laboratory medicine.Clinica chimica acta; international journal of clinical chemistry · 2016
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Eric WenzlerCollege of Pharmacy, University of Illinois at Chicago, Chicago, IL 60612, USA. Wenzler@uic.edu.
Jordan R WongDepartment of Pharmacy, Grady Health System, Atlanta, GA 30303, USA. JWong@gmh.edu.
Debra A GoffDepartment of Pharmacy, The Ohio State University, Wexner Medical Center, Columbus, OH 43210, USA. Debbie.Goff@osumc.edu.
Christopher A JankowskiDepartment of Pharmacy, University of Florida Health Jacksonville, Jacksonville, FL 32209, USA. Christopher.Jankowski@jax.ufl.edu.
Karri A BauerDepartment of Pharmacy, The Ohio State University, Wexner Medical Center, Columbus, OH 43210, USA. Karri.Bauer@osumc.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antimicrobial stewardship programs (ASPs) are challenged with ensuring appropriate antimicrobial use while minimizing expenditures. ASPs have consistently demonstrated improved patient outcomes and significant cost reductions but are continually required to justify the costs of their existence and interventions due to the silo mentality often adopted by hospital administrators. As new technologies and antimicrobials emerge, ASPs are in a constant tug-of-war between providing optimal clinical outcomes and ensuring cost containment. Additionally, robust data on cost-effectiveness of new rapid diagnostic technologies and antimicrobials with subsequent ASP interventions to provide justification are lacking. As the implementation of an ASP will soon be mandatory for acute care hospitals in the United States, ASPs must find ways to justify novel interventions to align themselves with healthcare administrators. This review provides a framework for the justification of implementing a rapid diagnostic test or adding a new antimicrobial to formulary with ASP intervention, reviews approaches to demonstrating cost-effectiveness, and proposes methods for which ASPs may reduce healthcare expenditures via alternative tactics.

Indexed as

antimicrobialoutcomesrapid diagnostic technologystewardship

Identifiers

PMID27025521
PMCPMC4810408

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.