ArticleMolecules (Basel, Switzerland)2016
Protective Effect of a (Poly)phenol-Rich Extract Derived from Sweet Cherries Culls against Oxidative Cell Damage.
Article in Molecules (Basel, Switzerland), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
19 citing papers in PubMed.
- Assessing the Role of Dark Sweet Cherry (Nutrients · 2025Trial
- From "Maraschino" to Cell Cultures: A Deep Study onMolecules (Basel, Switzerland) · 2025Article
- Oxidative Stress in Poultry and the Therapeutic Role of Herbal Medicine in Intestinal Health.Antioxidants (Basel, Switzerland) · 2024Review
- Review
- The use of African medicinal plants in cancer management.Frontiers in pharmacology · 2023Review
- Disclosing the Antioxidant and Neuroprotective Activity of an Anthocyanin-Rich Extract from Sweet Cherry (Antioxidants (Basel, Switzerland) · 2022Article
- Anti-Inflammatory and Antiproliferative Properties of Sweet Cherry Phenolic-Rich Extracts.Molecules (Basel, Switzerland) · 2022Article
- Polysaccharides from Garlic Protect against Liver Injury in DSS-Induced Inflammatory Bowel Disease of Mice via Suppressing Pyroptosis and Oxidative Damage.Oxidative medicine and cellular longevity · 2022Article
- Cherry Polyphenol Extract Ameliorated Dextran Sodium Sulfate-Induced Ulcerative Colitis in Mice by Suppressing Wnt/β-Catenin Signaling Pathway.Foods (Basel, Switzerland) · 2021Article
- Hepatoprotective Effects of Sweet Cherry Extracts (cv. Saco).Foods (Basel, Switzerland) · 2021Article
- Rootstock Affects the Fruit Quality of 'Early Bigi' Sweet Cherries.Foods (Basel, Switzerland) · 2021Article
- Sweet Cherries as Anti-Cancer Agents: From Bioactive Compounds to Function.Molecules (Basel, Switzerland) · 2021Review
- Fruit Quality Characterization of New Sweet Cherry Cultivars as a Good Source of Bioactive Phenolic Compounds with Antioxidant and Neuroprotective Potential.Antioxidants (Basel, Switzerland) · 2020Article
- Protective Effects of Some Grapevine Polyphenols against Naturally Occurring Neuronal Death.Molecules (Basel, Switzerland) · 2020Article
- Novel insights in health-promoting properties of sweet cherries.Journal of functional foods · 2020Article
- Antioxidant Effect of Cocoa By-Product and Cherry Polyphenol Extracts: A Comparative Study.Antioxidants (Basel, Switzerland) · 2020Article
- Chitosan-Based Nanoparticles Containing Cherry Extract fromNutrients · 2018Article
- Anti-Inflammatory Effect of a Polyphenol-Enriched Fraction fromOxidative medicine and cellular longevity · 2018Article
- Factors Affecting Quality and Health Promoting Compounds during Growth and Postharvest Life of Sweet Cherry (Frontiers in plant science · 2017Review
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Oxidative stress is one of the key phenomena behind the most common types of chronic diseases. Therefore, the modulation of oxidative stress is an interesting target for acting either through prevention or as a therapeutic approach. In this work, a Portuguese variety of cherry (Saco Cherry) was processed in order to obtain a potent in vitro antioxidant phenolic-rich extract (Ch-PRE), which was further explored to evaluate its potential application as nutraceutical agent against cellular oxidative stress damage. Ch-PRE was mainly composed of anthocyanins, particularly cyanidin-3-rutinoside, cyanidin-3-glucoside, peonidin-3-glucoside and neochlorogenic acid, and exhibited a potent chemical antioxidant activity expressed by its oxygen radical absorbance capacity (ORAC) and hydroxyl radical averting capacity (HORAC) values. Ch-PRE also displayed effective intracellular radical scavenging properties in intestinal epithelial and neuronal cells challenged with oxidative stress but showed a different order of effectiveness regarding the modulation of endogenous antioxidant system. Ch-PRE could be an attractive candidate to formulate an agent for the prevention of oxidative stress-induced disorders such as intestinal inflammation disorders or with an appropriated delivery system for neurodegenerative diseases.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.