ReviewPlant reproduction2016
Unfolded protein response in pollen development and heat stress tolerance.
Review in Plant reproduction, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
44 citing papers in PubMed.
- Comparative transcriptome analysis reveals stress-response pathways as key drivers of nitrogen use efficiency in tobacco under low-nitrogen conditions.BMC plant biology · 2026Article
- Anther and pollen thermotolerance: molecular mechanisms and implications for plant reproduction under heat stress.Planta · 2026Review
- Digital Monitoring and Modeling of Honey Bee Foraging on Clover Flowers Under Heat Stress.microPublication biology · 2026Article
- OsLEML2 Regulates Rice Thermotolerance Through Auxin and ROS Homeostasis.Rice (New York, N.Y.) · 2025Article
- Unresolved ER stress restricts in vitro plant cell totipotency.Plant cell reports · 2025Article
- Priming thermotolerance: unlocking heat resilience for climate-smart crops.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025Review
- Pollen transcriptomic analysis provided insights into understanding the molecular mechanisms underlying grafting-induced improvement in potato fertility.Frontiers in plant science · 2024Article
- Stimulus-responsive proteins involved in multi-process regulation of storage substance accumulation during rice grain filling under elevated temperature.BMC plant biology · 2023Article
- CRISPR-Cas-mediated unfolded protein response control for enhancing plant stress resistance.Frontiers in plant science · 2023Review
- Development of a GFP biosensor reporter for the unfolded protein response-signaling pathway in plants: incorporation of the bZIP60 intron into the GFP gene.Plant signaling & behavior · 2022Article
- Heat stress leads to rapid lipid remodeling and transcriptional adaptations in Nicotiana tabacum pollen tubes.Plant physiology · 2022Article
- Article
- HsfA1a confers pollen thermotolerance through upregulating antioxidant capacity, protein repair, and degradation inHorticulture research · 2022Article
- Tissue-specific transcriptomic analysis uncovers potential roles of natural antisense transcripts inFrontiers in plant science · 2022Article
- Long-Term Mild Heat Causes Post-Mitotic Pollen Abortion Through a Local Effect on Flowers.Frontiers in plant science · 2022Article
- Heat-induced proteomic changes in anthers of contrasting rice genotypes under variable stress regimes.Frontiers in plant science · 2022Article
- Rapid Transcriptional Reprogramming Associated With Heat Stress-Induced Unfolded Protein Response in DevelopingFrontiers in plant science · 2022Article
- Heat Stress-Mediated Constraints in Maize (Frontiers in plant science · 2022Review
- Circular RNAs Repertoire and Expression Profile duringInternational journal of molecular sciences · 2021Article
- Insights into the Mechanisms of Heat Priming and Thermotolerance in Tobacco Pollen.International journal of molecular sciences · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
key messageImportance of the UPR for pollen. Pollen is particularly sensitive to environmental conditions that disturb protein homeostasis, such as higher temperatures. Their survival is dependent on subcellular stress response systems, one of which maintains protein homeostasis in the endoplasmic reticulum (ER). Disturbance of ER proteostasis due to stress leads to the activation of the unfolded protein response (UPR) that mitigates stress damage mainly by increasing ER-folding capacity and reducing folding demands. The UPR is controlled by ER membrane-associated transcription factors and an RNA splicing factor. They are important components of abiotic stress responses including general heat stress response and thermotolerance. In addition to responding to environmental stresses, the UPR is implicated in developmental processes required for successful male gametophyte development and fertilization. Consequently, defects in the UPR can lead to pollen abortion and male sterility. Several UPR components are involved in the elaboration of the ER network, which is required for pollen germination and polar tube growth. Transcriptome and proteome analyses have shown that components of the ER-folding machinery and the UPR are upregulated at specific stages of pollen development supporting elevated demands for secretion. Furthermore, genetic studies have revealed that knockout mutants of UPR genes are defective in producing viable or competitive pollen. In this review, we discuss recent findings regarding the importance of the UPR for both pollen development and stress response.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.