ArticleEnvironmental health perspectives2016
Exposure to Traffic-Related Air Pollution in Relation to Progression in Physical Disability among Older Adults.
Article in Environmental health perspectives, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 2 of them syntheses that pooled it.
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Who cites it
32 citing papers in PubMed, 2 syntheses or guidelines pooled it, 63 citations in OpenAlex.
- Exposure to Air Pollution in Relation to Risk of Dementia and Related Outcomes: An Updated Systematic Review of the Epidemiological Literature.Environmental health perspectives · 2021Pooled it
- Exposure to air pollution as a potential contributor to cognitive function, cognitive decline, brain imaging, and dementia: A systematic review of epidemiologic research.Neurotoxicology · 2016Pooled it
- Disparities in fine particulate matter (PMEnvironmental research, health : ERH · 2026Article
- Residential aircraft and road noise exposure, cognition, and Alzheimer's dementia in a US cohort of older adults.Environmental epidemiology (Philadelphia, Pa.) · 2026Article
- Seasonal green space, air pollution, and temperature in the United States: Spatial disparities among people with disabilities.The Science of the total environment · 2026Article
- Associations of PMBMC public health · 2026Article
- Air Pollution and the Progression of Physical Function Limitations and Disability in Aging Adults.JAMA network open · 2026Article
- Long-term air pollution exposure and gait speed decline among older Adults: A longitudinal analysis.Environmental research · 2026Article
- Air pollution exposure among people with limitations in activities of daily living in the United States.medRxiv : the preprint server for health sciences · 2025Article
- Traffic-related air pollutant exposure and physical performance in the Adult Changes in Thought cohort.Environment international · 2025Article
- Intercomparison of Modeled Urban-Scale Vehicle NOEnvironmental science & technology · 2025Article
- Outdoor nitrogen dioxide exposure and longitudinal health status trajectory in the Canadian National Population Health Survey.Scientific reports · 2024Article
- Association of Tailpipe-Related and Nontailpipe-Related Air Pollution Exposure with Cognitive Decline in the Chicago Health and Aging Project.Environmental health perspectives · 2024Article
- Long-term air pollution exposure and incident physical disability in older US adults: a cohort study.The lancet. Healthy longevity · 2024Article
- Source-Specific Air Pollution and Loss of Independence in Older Adults Across the US.JAMA network open · 2024Article
- Traffic related activity pattern of Chinese adults: a nation-wide population based survey.Journal of exposure science & environmental epidemiology · 2023Article
- Exploring the relationship between air quality and health shocks to the elderly: A retrospective cross-sectional study in China.Frontiers in public health · 2023Article
- Associations of Heavy Metals with Activities of Daily Living Disability: An Epigenome-Wide View of DNA Methylation and Mediation Analysis.Environmental health perspectives · 2022Article
- Residential proximity to major roadway and progression in physical disability in older adults in China.Environmental science and pollution research international · 2022Article
- Associations of Household Solid Fuel Use With Falls and Fall-Related Injuries in Middle-Aged and Older Population in China: A Cohort Study.International journal of public health · 2022Article
Corrections and comments
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Authors and funding
8 authors at 5 institutions in 1 country.
Funding
Abstract
backgroundPhysical disability is common though not inevitable in older age and has direct bearing on a person's ability to perform activities essential for self-care and independent living. Air pollution appears to increase the risk of several chronic diseases that contribute to the progression of disability.
objectiveWe evaluated long-term exposure to traffic-related air pollution (TRAP) in relation to progression in physical disability.
methodsWe conducted our investigation within the Chicago Health and Aging Project. We measured participants' exposures to TRAP using two surrogates: residential proximity to major roads (1993 onwards) and ambient concentrations of oxides of nitrogen (NOX; 1999 onwards), predicted via a geographic information systems-based spatiotemporal smoothing model (cross-validation R2 = 0.87) that incorporated community-based monitoring and resolved intraurban exposure gradients at a spatial scale of tens of meters. Participants' lower-extremity physical ability was assessed every 3 years (1993-2012) via tandem stand, chair stand, and timed walking speed.
resultsIn multivariable-adjusted analyses (n = 5,708), higher long-term NOX exposure was associated with significantly faster progression in disability. Compared with the 5-year decline in physical ability score among participants in the lowest quartile of NOX exposure, decline among those in the highest exposure quartile was 1.14 units greater (95% confidence interval [CI]: -1.86, -0.42), equivalent to 3 additional years of decline among those in the lowest exposure quartile. The association was linear across the continuum of NOX exposure: per 10-ppb increment in exposure, the 5-year decline in physical ability score was 0.87 unit greater (95% CI: -1.35, -0.39). Proximity to a major road was not associated with disability progression (n = 9,994).
conclusionsThese data join a growing body of evidence suggesting that TRAP exposures may accelerate aging-related declines in health. CITATION: Weuve J, Kaufman JD, Szpiro AA, Curl C, Puett RC, Beck T, Evans DA, Mendes de Leon CF. 2016. Exposure to traffic-related air pollution in relation to progression in physical disability among older adults. Environ Health Perspect 124:1000-1008; http://dx.doi.org/10.1289/ehp.1510089.
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