Evidence map›Paper›PMID 27022859›Full record

ReviewCurrent opinion in pharmacology2016

Bone marrow adipose tissue: formation, function and regulation.

Karla J Suchacki, William P Cawthorn, Clifford J Rosen

Abstract readReview
In one paragraph

Review in Current opinion in pharmacology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. The Sequential Therapy in Osteoporosis.Indian journal of orthopaedics · 2023
    Review
  12. Article
  13. Review
  14. Review
  15. Review
  16. Article
  17. Libanoridin Isolated fromInternational journal of molecular sciences · 2022
    Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Karla J SuchackiThe Queen's Medical Research Institute, University of Edinburgh, UK. Electronic address: ksuchack@exseed.ed.ac.uk.
William P CawthornThe Queen's Medical Research Institute, University of Edinburgh, UK.
Clifford J RosenMaine Medical Center Research Institute, Scarborough, ME, USA.

Funding

Interdisciplinary Study of Marrow Adiposity, Mineral Metabolism & Energy BalanceR24DK092759 · NIDDK · MAINEHEALTH · PI HOROWITZ, MARK C, MACDOUGALD, ORMOND A · 2011 to 2019
$13.0M
Medical Research Council MR/M021394/1NIDDK NIH HHS R24 DK092759
6 · The paper itself

Abstract

The human body requires an uninterrupted supply of energy to maintain metabolic homeostasis and energy balance. To sustain energy balance, excess consumed calories are stored as glycogen, triglycerides and protein, allowing the body to continue to function in states of starvation and increased energy expenditure. Adipose tissue provides the largest natural store of excess calories as triglycerides and plays an important role as an endocrine organ in energy homeostasis and beyond. This short review is intended to detail the current knowledge of the formation and role of bone marrow adipose tissue (MAT), a largely ignored adipose depot, focussing on the role of MAT as an endocrine organ and highlighting the pharmacological agents that regulate MAT.

Indexed as

Adipose TissueAnimalsBone MarrowEnergy IntakeEnergy MetabolismGlycogenHomeostasisHumansProteinsTriglyceridesGlycogenProteinsTriglycerides

Identifiers

PMID27022859
PMCPMC5351553

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.