ArticleInflammation2016
Analysis of Soluble Molecular Fibronectin-Fibrin Complexes and EDA-Fibronectin Concentration in Plasma of Patients with Atherosclerosis.
Article in Inflammation, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 33 citations in OpenAlex.
- Increased plasma fibronectin mirrors intimal phenotypic switching of vascular smooth muscle cells in moyamoya arteriopathy.Scientific reports · 2025Article
- Review
- Changes in various forms of fibronectin in patients undergoing coronary artery bypass grafting with cardiopulmonary bypass - a prospective, observational study.Scientific reports · 2024Observational
- Interactions of Fibroblast Subtypes Influence Osteoclastogenesis and Alveolar Bone Destruction in Periodontitis.Journal of inflammation research · 2023Article
- Different roles of endothelial cell-derived fibronectin and plasma fibronectin in endothelial dysfunction.Turkish journal of medical sciences · 2023Article
- Explainable Artificial Intelligence Helps in Understanding the Effect of Fibronectin on Survival of Sepsis.Cells · 2022Article
- Article
- Bioinformatics and Machine Learning Methods to Identify FN1 as a Novel Biomarker of Aortic Valve Calcification.Frontiers in cardiovascular medicine · 2022Article
- Elevated plasma EDA fibronectin in primary myelofibrosis is determined by high allele burden ofFrontiers in oncology · 2022Article
- Fibronectin Molecular Status in Plasma of Women with Endometriosis and Fertility Disorders.International journal of molecular sciences · 2021Article
- Cellular fibronectin promotes deep vein thrombosis in diet-induced obese mice.Journal of thrombosis and haemostasis : JTH · 2021Article
- Differential Roles of Endothelial Cell-Derived and Smooth Muscle Cell-Derived Fibronectin Containing Extra Domain A in Early and Late Atherosclerosis.Arteriosclerosis, thrombosis, and vascular biology · 2020Article
- Smooth muscle cell-specific fibronectin-EDA mediates phenotypic switching and neointimal hyperplasia.The Journal of clinical investigation · 2020Article
- Changes of plasma fibronectin and fibronectin-fibrin complexes in dams of stillborn dairy calves.Irish veterinary journal · 2020Article
- Comparative Platelet Releasate Proteomic Profiling of Acute Coronary Syndrome versus Stable Coronary Artery Disease.Frontiers in cardiovascular medicine · 2020Article
- Extracellular Matrix Remodeling Factors as Markers of Carotid Artery Atherosclerosis.Cardiology research and practice · 2020Article
- Plasma and Cellular Forms of Fibronectin as Prognostic Markers in Sepsis.Mediators of inflammation · 2020Article
- Bevacizumab or fibronectin gene editing inhibits the osteoclastogenic effects of fibroblasts derived from human radicular cysts.Acta pharmacologica Sinica · 2019Article
- Article
- Time-dependent changes in extra-domain A-fibronectin concentration and relative amounts of fibronectin-fibrin complexes in plasma of patients with peripheral arterial disease after endovascular revascularisation.International wound journal · 2018Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Atherosclerosis, a chronic vascular disease, leads to molecular events bound with interplaying processes of inflammation and coagulation. In the present study, fibronectin (FN), FN containing extra domain A (EDA-FN), frequency of occurrence, and relative amounts of soluble plasma FN-fibrin complexes were analyzed in 80 plasma samples of patients suspected of coronary artery disease based on clinical evaluation and changes in arteries found by computed tomographic coronary angiography. The study showed that in the plasma of the patients' group with high risk of coronary artery disease EDA-FN concentration was significantly higher (3.5 ± 2.5 mg/L; P < 0.025) and the molecular FN-fibrin complexes of 1000 kDa and higher occurred more often than in the groups of patients with mild risk of coronary artery disease and the normal age-matched. The increased level of EDA-FN and occurrence of FN-fibrin complexes could have a potential diagnostic value in the diagnosis and management of patients with coronary artery disease.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.