Evidence map›Paper›PMID 27022461›Full record

ArticleWorld journal of cardiology2016

Typical rise and fall of troponin in (peri-procedural) myocardial infarction: A systematic review.

Dianne van Beek, Bas van Zaane, Marjolein Looije, Linda Peelen, Wilton van Klei

Open access · hybridAbstract read
In one paragraph

Article in World journal of cardiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
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  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Dianne van BeekDianne van Beek, Bas van Zaane, Linda Peelen, Wilton van Klei, Department of Anesthesiology, University Medical Center Utrecht, 3508 GA Utrecht, The Netherlands.
Bas van ZaaneDianne van Beek, Bas van Zaane, Linda Peelen, Wilton van Klei, Department of Anesthesiology, University Medical Center Utrecht, 3508 GA Utrecht, The Netherlands.
Marjolein LooijeDianne van Beek, Bas van Zaane, Linda Peelen, Wilton van Klei, Department of Anesthesiology, University Medical Center Utrecht, 3508 GA Utrecht, The Netherlands.
Linda PeelenDianne van Beek, Bas van Zaane, Linda Peelen, Wilton van Klei, Department of Anesthesiology, University Medical Center Utrecht, 3508 GA Utrecht, The Netherlands.
Wilton van KleiDianne van Beek, Bas van Zaane, Linda Peelen, Wilton van Klei, Department of Anesthesiology, University Medical Center Utrecht, 3508 GA Utrecht, The Netherlands.
University Medical Center Utrecht · NLCreative Research Enterprises (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo identify the typical shape of the rise and fall curve of troponin (Tn) following the different types of myocardial infarction (MI).

methodsWe conducted a systematic search in PubMed and Embase including all studies which focused on the kinetics of Tn in MI type 1, type 4 and type 5. Tn levels were standardized using the 99(th) percentile, a pooled mean with 95%CI was calculated from the weighted means for each time point until 72 h.

resultsA total of 34 of the 2528 studies identified in the systematic search were included. The maximum peak level of the Tn was seen after 6 h after successful reperfusion of an acute MI, after 12 h for type 1 MI and after 72 h for type 5 MI. In type 1 MI there were additional smaller peaks at 1 h and at 24 h. After successful reperfusion of an acute MI there was a second peak at 24 h. There was not enough data available to analyze the Tn release after MI associated with percutaneous coronary intervention (type 4).

conclusionThe typical rise and fall of Tn is different for type 1 MI, successful reperfusion of an acute MI and type 5 MI, with different timing of the peak levels and different slopes of the fall phase.

Indexed as

Coronary artery bypass graftingMyocardial infarctionReperfusionSystematic reviewTroponin

Identifiers

PMID27022461
PMCPMC4807318
OpenAlexW2317205035

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.