Evidence map›Paper›PMID 27022342›Full record

ArticlePakistan journal of medical sciences

Comparison of blood and urine nephrin levels in preeclampsia and intrauterine growth retardation.

Fatma Ozdemir, Ahter Tanay Tayyar, Gokhan Acmaz, Huseyin Aksoy, Gozde Erturk, Sabahattin Muhtaroglu, Mehmet Tayyar

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pakistan journal of medical sciences. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Podocytes-The Most Vulnerable Renal Cells in Preeclampsia.International journal of molecular sciences · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Fatma OzdemirFatma Ozdemir, MD, Department of Obstetrics and Gynecology, Education and Research Hospital, Kayseri, Turkey.
Ahter Tanay TayyarAhter Tanay Tayyar, MD, Department of Obstetrics and Gynecology, Private Erciyes Hospital, Kayseri, Turkey.
Gokhan AcmazGokhan Acmaz, MD, Department of Obstetrics and Gynecology, Education and Research Hospital, Kayseri, Turkey.
Huseyin AksoyHuseyin Aksoy, MD, Department of Obstetrics and Gynecology, Military Hospital, Kayseri, Turkey.
Gozde ErturkGozde Erturk, Department of Biostatistics, Erciyes University Faculty of Medicine, Kayseri, Turkey.
Sabahattin MuhtarogluDr. Sabahattin Muhtaroglu, Professor, Department of Biochemistry, Erciyes University Faculty of Medicine, Kayseri, Turkey.
Mehmet TayyarDr. Mehmet Tayyar Professor, Department of Obstetrics and Gynecology, Erciyes University Faculty of Medicine, Kayseri, Turkey.
Erciyes University · TREducation Training And Research · USKayseri Eğitim ve Araştırma Hastanesi · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the relation between nephrin levels and preeclampsia severity by comparing serum and urine levels of nephrin in the severe and mild groups according to severity of associated intrauterine growth retardation (IUGR) development.

methodsA total of 150 patients who attended our ante-natal clinic (ANC) were included in this study. We had 5 groups; Group 1:30 patients with mild preeclampsia (MP) and normal fetal development (NFD), Group 2:30 patients with severe preeclampsia (SP) and NFD, Group 3: 30 patients with MP and IUGR, Group 4: 30 patients with SP and IUGR and Group 5: 30 volunteers who were normotensive and non-preeclamptic. We obtained both blood and urine samples for measuring nephrin levels.

resultsBoth serum and urine nephrin levels were significantly higher for the fourth group compared with all other groups (p<0.001). The levels of SP group with NFD were measured considerably higher than MP group out of IUGR and control group (p<0.001). Urine and serum nephrin levels with gestational age of delivery showed a negative correlation (r=-0.621, p<0.001) and also urine and serum nephrin levels with birth weight showed a negative correlation too (r=-0.655 p<0.001).

conclusionBoth serum and urine nephrin levels correlated with the severity of preeclampsia and IUGR development.

Indexed as

Intrauterine growth retardationPreeclampsiaSerum NephrinUrine Nephrin

Identifiers

PMID27022342
PMCPMC4795886
OpenAlexW2463549768

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.