Evidence map›Paper›PMID 27022064›Full record

ArticleCirculation2016

Menthol and Nonmenthol Cigarette Smoking: All-Cause Deaths, Cardiovascular Disease Deaths, and Other Causes of Death Among Blacks and Whites.

Heather M Munro, Robert E Tarone, Thomas J Wang, William J Blot

Open access · bronzeAbstract read
In one paragraph

Article in Circulation, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Association of Urinary Biomarkers of Tobacco Exposure with Lung Cancer Risk in African American and White Cigarette Smokers in the Southern Community Cohort Study.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2024
    Article
  5. Article
  6. Article
  7. Comparison of Carcinogen Biomarkers in Smokers of Menthol and Nonmenthol Cigarettes: The 2015-2016 National Health and Nutrition Examination Survey Special Sample.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2022
    Article
  8. Article
  9. Role of l- and d-Menthol in the Glucuronidation and Detoxification of the Major Lung Carcinogen, NNAL.Drug metabolism and disposition: the biological fate of chemicals · 2019
    Article
  10. Flavorings in Tobacco Products Induce Endothelial Cell Dysfunction.Arteriosclerosis, thrombosis, and vascular biology · 2018
    Article
  11. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Heather M MunroFrom International Epidemiology Institute, Rockville, MD (H.M.M., R.E.T., W.J.B.); and Department of Medicine, Vanderbilt University Medical Center, Nashville, TN (T.J.W., W.J.B.).
Robert E TaroneFrom International Epidemiology Institute, Rockville, MD (H.M.M., R.E.T., W.J.B.); and Department of Medicine, Vanderbilt University Medical Center, Nashville, TN (T.J.W., W.J.B.).
Thomas J WangFrom International Epidemiology Institute, Rockville, MD (H.M.M., R.E.T., W.J.B.); and Department of Medicine, Vanderbilt University Medical Center, Nashville, TN (T.J.W., W.J.B.).
William J BlotFrom International Epidemiology Institute, Rockville, MD (H.M.M., R.E.T., W.J.B.); and Department of Medicine, Vanderbilt University Medical Center, Nashville, TN (T.J.W., W.J.B.). blotw@iei.us.
International Epidemiology Institute · US

Funding

Southern Community Cohort StudyR01CA092447 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BLOT, WILLIAM J., ZHENG, WEI · 2001 to 2015
$74.0M
NCI NIH HHS R01 CA092447
6 · The paper itself

Abstract

backgroundIn contrast to whites, black smokers prefer menthol cigarettes over nonmenthol cigarettes by a large margin and tend to have higher mortality from several smoking-related diseases than whites, raising the possibility that menthol cigarettes contribute to racial disparities in risk. Evidence for differential associations between menthol and nonmenthol cigarettes indicates lower cancer risk for menthol smokers, but for cardiovascular disease (CVD) mortality, evidence has been inconsistent. METHODS AND

resultsCox proportional hazards models were used to compute hazard ratios and accompanying 95% confidence intervals for all-cause and CVD mortality for menthol compared with nonmenthol cigarette smokers among 65 600 participants in the Southern Community Cohort Study, an ongoing community-based cohort with the largest number of menthol smokers being traced. Among the 27 619 current cigarette smokers, 4224 died during follow-up, with 1130 deaths attributed to CVD. Both all-cause (hazard ratio=0.93; 95% confidence interval=0.86-1.01; P=0.10) and CVD (hazard ratio=0.88; 95% confidence interval=0.76-1.03; P=0.10) mortality risks were similar in menthol compared with nonmenthol cigarette smokers.

conclusionsSmoking regardless of cigarette type is hazardous to health, but these results do not indicate that menthol cigarettes are associated with greater CVD risks than nonmenthol cigarettes.

Indexed as

Black PeopleWhite PeopleAdultAgedBlack or African AmericanCardiovascular DiseasesCohort StudiesFemaleFollow-Up StudiesHealthcare DisparitiesHumansMaleMentholMiddle AgedProspective StudiesSmokingMentholcardiovascular diseasesepidemiologymortalitysmoking

Identifiers

PMID27022064
PMCPMC4886344
OpenAlexW2325842883

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.