ArticleAntimicrobial agents and chemotherapy2016
dfrA thyA Double Deletion in para-Aminosalicylic Acid-Resistant Mycobacterium tuberculosis Beijing Strains.
Abstract read
In one paragraph
Article in Antimicrobial agents and chemotherapy, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed.
- Mutations inJAC-antimicrobial resistance · 2026Article
- Overexpression of outer membrane protein A (OmpA) increases aminoglycoside sensitivity in mycobacteria.BMC microbiology · 2024Article
- Integrating bacterial molecular genetics with chemical biology for renewed antibacterial drug discovery.The Biochemical journal · 2024Review
- Competition between HAntibiotics (Basel, Switzerland) · 2023Article
- Whole genome sequencing reveals large deletions and other loss of function mutations inMicrobial genomics · 2021Article
- A biochemically-interpretable machine learning classifier for microbial GWAS.Nature communications · 2020Article
- PARMAP: A Pan-Genome-Based Computational Framework for Predicting Antimicrobial Resistance.Frontiers in microbiology · 2020Article
- Article
- Drugging the Folate Pathway in Mycobacterium tuberculosis: The Role of Multi-targeting Agents.Cell chemical biology · 2019Article
- Revitalizing antifolates through understanding mechanisms that govern susceptibility and resistance.MedChemComm · 2019Review
- Genome-wide analysis of Mycobacterium tuberculosis polymorphisms reveals lineage-specific associations with drug resistance.BMC genomics · 2019Article
- Integrating standardized whole genome sequence analysis with a global Mycobacterium tuberculosis antibiotic resistance knowledgebase.Scientific reports · 2018Article
- Machine learning and structural analysis of Mycobacterium tuberculosis pan-genome identifies genetic signatures of antibiotic resistance.Nature communications · 2018Article
- Deletion ofAntimicrobial agents and chemotherapy · 2017Article
- Mycobacterium tuberculosis resistance prediction and lineage classification from genome sequencing: comparison of automated analysis tools.Scientific reports · 2017Article
- The variability and reproducibility of whole genome sequencing technology for detecting resistance to anti-tuberculous drugs.Genome medicine · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors.
Danesh MoradigaravandWellcome Trust Sanger Institute, Hinxton, United Kingdom.
Louis GrandjeanWellcome Centre for Clinical Tropical Medicine, Imperial College London, St. Mary's Campus, London, United Kingdom London School of Hygiene and Tropical Medicine, London, United Kingdom Laboratorio de Investigación en Enfermedades Infecciosas, Universidad Peruana Cayetano Heredia, Lima, Peru.
Elena MartinezCentenary Institute and Marie Bashir Institute for Infectious Diseases and Biosecurity, The University of Sydney, Sydney, Australia NSW Mycobacterium Reference Laboratory, Centre for Infectious Diseases and Microbiology Laboratory Services, Institute of Clinical Pathology and Medical Research-Pathology West, Sydney, Australia Centre for Infectious Diseases and Microbiology-Public Health, Westmead Hospital, Western Sydney Local Health District, Sydney, Australia.
Hao LiCollaborative Innovation Centre for the Diagnosis and Treatment of Infectious Diseases, School of Medicine, Tsinghua University, Beijing, China.
Jun ZhengFaculty of Health Sciences, University of Macau, Macau SAR, China.
Jorge CoronelLaboratorio de Investigación en Enfermedades Infecciosas, Universidad Peruana Cayetano Heredia, Lima, Peru.
David MooreLondon School of Hygiene and Tropical Medicine, London, United Kingdom Laboratorio de Investigación en Enfermedades Infecciosas, Universidad Peruana Cayetano Heredia, Lima, Peru.
M Estée TörökDepartment of Medicine, University of Cambridge, Cambridge, United Kingdom Department of Infectious Diseases, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom Clinical Microbiology and Public Health Laboratory, Public Health England, Cambridge, United Kingdom.
Vitali SintchenkoCentenary Institute and Marie Bashir Institute for Infectious Diseases and Biosecurity, The University of Sydney, Sydney, Australia NSW Mycobacterium Reference Laboratory, Centre for Infectious Diseases and Microbiology Laboratory Services, Institute of Clinical Pathology and Medical Research-Pathology West, Sydney, Australia Centre for Infectious Diseases and Microbiology-Public Health, Westmead Hospital, Western Sydney Local Health District, Sydney, Australia.
Hairong HuangNational Clinical Laboratory on Tuberculosis, Beijing Key Laboratory on Drug-Resistant Tuberculosis Research, Beijing Chest Hospital, Capital Medical University, Beijing Tuberculosis and Thoracic Tumor Institute, Beijing, China.
Babak JavidCollaborative Innovation Centre for the Diagnosis and Treatment of Infectious Diseases, School of Medicine, Tsinghua University, Beijing, China Department of Medicine, University of Cambridge, Cambridge, United Kingdom.ORCID 0000-0002-6354-6305
Julian ParkhillWellcome Trust Sanger Institute, Hinxton, United Kingdom.ORCID 0000-0002-7069-5958
Sharon J PeacockWellcome Trust Sanger Institute, Hinxton, United Kingdom London School of Hygiene and Tropical Medicine, London, United Kingdom Department of Medicine, University of Cambridge, Cambridge, United Kingdom.
Claudio U KöserDepartment of Medicine, University of Cambridge, Cambridge, United Kingdom cuk21@cam.ac.uk.ORCID 0000-0002-0232-846X
Funding
Department of HealthMedical Research Council MR/N029399/1Wellcome Trust 098600
Abstract
PubMed holds no abstract for this paper.
Indexed as
Drug Resistance, BacterialAminosalicylic AcidAntitubercular AgentsBacterial ProteinsChinaGenotypeHumansMicrobial Sensitivity TestsMycobacterium tuberculosisSequence DeletionTuberculosisAminosalicylic AcidAntitubercular AgentsBacterial Proteins
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.