Evidence map›Paper›PMID 27020720›Full record

Trial reportAsia-Pacific psychiatry : official journal of the Pacific Rim College of Psychiatrists2016

The effectiveness and safety of amisulpride in Chinese patients with schizophrenia: An 8-week, prospective, open-label, multicenter, single-arm study.

Ying Liang, Changan Cao, Cheng Zhu, Chuanyue Wang, Congpei Zhang, Fang Dong, Fude Yang, Hong Deng, Jingjie Yu, Jisheng Tang and 16 more

Registry-linked trialOpen access · hybridAbstract readClinical Trial, Phase IVMulticenter Study
In one paragraph

Trial report in Asia-Pacific psychiatry : official journal of the Pacific Rim College of Psychiatrists, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01795183 (The Effectiveness and Safety of Amisulpride in Chinese Patients With Schizophrenia - A Prospective Open-Label Multicenter Study), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01795183 phase4completednot on this map

The Effectiveness and Safety of Amisulpride in Chinese Patients With Schizophrenia - A Prospective Open-Label Multicenter Study

TypeinterventionalSponsorSanofiRan2012 to 2013Enrolled316ConditionsSchizophreniaArmsAMISULPRIDE
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors at 17 institutions in 1 country.

Ying LiangNational Clinical Research Center for Mental Disorders, Peking University Sixth Hospital, Institute of Mental Health, and the Key Laboratory of Mental Health, Ministry of Health, Peking University, Beijing, China.
Changan CaoDepartment of Psychiatry, Shenzhen Kangning Hospital, Shenzhen, China.
Cheng ZhuDepartment of Psychiatry, The Seventh People Hospital of Hangzhou, Hangzhou, China.
Chuanyue WangDepartment of Psychiatry, Beijing An Ding Hospital, Capital Medical University, Beijing, China.
Congpei ZhangDepartment of Psychiatry, The First Special Hospital of Harbin, Harbin, China.
Fang DongDepartment of Psychiatry, Beijing An Ding Hospital, Capital Medical University, Beijing, China.
Fude YangDepartment of Psychiatry, Beijing Huilongguan Hospital, Beijing, China.
Hong DengDepartment of Psychiatry, West China Hospital, Sichuan University, Chengdu, China.
Jingjie YuDepartment of Psychiatry, Tianjin Anding hospital, Tianjin, China.
Jisheng TangDepartment of Psychiatry, Mental Health Centre of Shandong Province, Jinan, China.
Lei SuDepartment of Psychiatry, Mental Health Centre of Shandong Province, Jinan, China.
Limin XinDepartment of Psychiatry, Beijing Huilongguan Hospital, Beijing, China.
Ling HongDepartment of Psychiatry, West China Hospital, Sichuan University, Chengdu, China.
Minglong GaoDepartment of Psychiatry, The First Hospital of Hebei Medical University, Shijiazhuang, China.
Muni TangDepartment of Psychiatry, Guangzhou Brain Hospital, Guangzhou, China.
Shiping XieDepartment of Psychiatry, Nanjing Brain Hospital, Nanjing, China.
Shuiping LuDepartment of Psychiatry, Nanjing Brain Hospital, Nanjing, China.
Tiebang LiuDepartment of Psychiatry, Shenzhen Kangning Hospital, Shenzhen, China.
Xiaojin XuDepartment of Psychiatry, Mental Health Center of Wu Han City, Wuhan, China.
Xijin WangDepartment of Psychiatry, The First Special Hospital of Harbin, Harbin, China.
Xuanzi LiDepartment of Psychiatry, Guangzhou Brain Hospital, Guangzhou, China.
Xueyi WangDepartment of Psychiatry, The First Hospital of Hebei Medical University, Shijiazhuang, China.
Yi LiDepartment of Psychiatry, Mental Health Center of Wu Han City, Wuhan, China.
Yong ZhangDepartment of Psychiatry, Tianjin Anding hospital, Tianjin, China.
Zhiyu ChenDepartment of Psychiatry, The Seventh People Hospital of Hangzhou, Hangzhou, China.
Xin YuNational Clinical Research Center for Mental Disorders, Peking University Sixth Hospital, Institute of Mental Health, and the Key Laboratory of Mental Health, Ministry of Health, Peking University, Beijing, China.
Beijing HuiLongGuan Hospital · CNHangzhou Seventh Peoples Hospital · CNHarbin Medical University · CNNanjing Brain Hospital · CNShandong Mental Health Center · CNShenzhen KangNing Hospital · CNSichuan University · CNTianjin Anding Hospital · CNWuhan Wudong Hospital · CNBeijing Anzhen Hospital · CNBeijing Ditan Hospital · CNFirst Affiliated Hospital of Hebei Medical University · CNGuangdong 999 Brain Hospital · CNGuangzhou Psychiatric Hospital · CNHebei Medical University · CNPeking University · CNPeking University Sixth Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThis study evaluated the effectiveness and safety of amisulpride in Chinese schizophrenia patients.

methodsA multicenter, single-arm Phase IV study (NCT01795183). Chinese patients with schizophrenia received amisulpride for 8 weeks. The primary endpoint was ≥50% decrease in Positive and Negative Syndrome Scale total score from Baseline to Week 8.

resultsA total of 316 patients were enrolled; 295 were included in the effectiveness analysis; 66.8% (197/295) achieved ≥50% decrease in Positive and Negative Syndrome Scale total score from Baseline to Week 8. Nine patients discontinued treatment because of adverse events. DISCUSSION: Amisulpride had clinical effectiveness and was relatively well tolerated in Chinese patients with schizophrenia.

Indexed as

AdolescentAdultAmisulprideAntipsychotic AgentsFemaleHumansMaleMiddle AgedProspective StudiesSchizophreniaSulpirideTreatment OutcomeYoung AdultAmisulprideAntipsychotic AgentsSulpirideamisulprideantipsychotic agents/adverse effectsantipsychotic agents/therapeutic useChineseSchizophrenia

Identifiers

PMID27020720
PMCPMC5071681
OpenAlexW2323894559

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.