Evidence map›Paper›PMID 27020455›Full record

ArticleProtein & cell2016

Phorbol myristate acetate suppresses breast cancer cell growth via down-regulation of P-Rex1 expression.

Chuu-Yun A Wong, Haihong Jiang, Peter W Abel, Margaret A Scofield, Yan Xie, Taotao Wei, Yaping Tu

Open access · diamondAbstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Protein & cell, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Chuu-Yun A WongDepartment of Pharmacology, Creighton University School of Medicine, Omaha, NE, 68178, USA.
Haihong JiangDepartment of Pharmacology, Creighton University School of Medicine, Omaha, NE, 68178, USA.
Peter W AbelDepartment of Pharmacology, Creighton University School of Medicine, Omaha, NE, 68178, USA.
Margaret A ScofieldDepartment of Pharmacology, Creighton University School of Medicine, Omaha, NE, 68178, USA.
Yan XieDepartment of Pharmacology, Creighton University School of Medicine, Omaha, NE, 68178, USA.
Taotao WeiNational Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China. weitt@moon.ibp.ac.cn.
Yaping TuDepartment of Pharmacology, Creighton University School of Medicine, Omaha, NE, 68178, USA. Yat60399@creighton.edu.
Creighton University · USInstitute of Biophysics · CN

Funding

UNMC Structural Biology CoreP20GM103427 · NIGMS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI Heather Colleen Jensen-Smith · 2012 to 2026
$59.2M
UNMC Histology/Imaging and Creighton University Imaging Core FacilityP30GM110768 · NIGMS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI SMITH, SHELLEY D · 2014 to 2018
$5.1M
Research Pilot Project ProgramP30GM106397 · NIGMS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI JOHNSON, KEITH R · 2013 to 2017
$4.9M
Nebraska Center for Cellular SignalingP20GM103489 · NIGMS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI JOHNSON, KEITH R · 2012 to 2012
$2.0M
NIGMS NIH HHS P20 GM103427NIGMS NIH HHS P20 GM103489NIGMS NIH HHS P30 GM106397NIGMS NIH HHS P30 GM110768
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Breast NeoplasmsCell Line, TumorCell ProliferationDown-RegulationErb-b2 Receptor Tyrosine KinasesFemaleGuanine Nucleotide Exchange FactorsHumansIndolesMaleimidesMCF-7 CellsProtein IsoformsProtein Kinase CRNA InterferenceRNA, Small InterferingTetradecanoylphorbol Acetate2-(1-(3-dimethylaminopropyl)-5-methoxyindol-3-yl)-3-(1H-indol-3-yl)maleimideERBB2 protein, humanErb-b2 Receptor Tyrosine KinasesGuanine Nucleotide Exchange FactorsIndolesMaleimidesPREX1 protein, humanProtein IsoformsProtein Kinase CRNA, Small InterferingTetradecanoylphorbol Acetate

Identifiers

PMID27020455
PMCPMC4887325
OpenAlexW2333345801

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.