Evidence map›Paper›PMID 27020292›Full record

ReviewApplied microbiology and biotechnology2016

Functions and importance of mycobacterial extracellular vesicles.

G Marcela Rodriguez, Rafael Prados-Rosales

Abstract readReview
In one paragraph

Review in Applied microbiology and biotechnology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Review
  2. Enhancement of mycobacterial pathogenesis by host interferon-γ.Cellular and molecular life sciences : CMLS · 2024
    Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Review
  8. International journal of molecular sciences · 2021
    Article
  9. Extracellular Metabolism Sets the Table for Microbial Cross-Feeding.Microbiology and molecular biology reviews : MMBR · 2021
    Review
  10. Article
  11. Review
  12. Review
  13. Cracking Open Bacterial Membrane Vesicles.Frontiers in microbiology · 2019
    Review
  14. Review
  15. A reevaluation of iron binding by Mycobactin J.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2018
    Article
  16. Mycobacterium avium Complex Extracellular Vesicles Attenuate Inflammation via Inducing IL-10.International journal of molecular and cellular medicine · 2018
    Article
  17. Review
  18. Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

G Marcela RodriguezPublic Health Research Institute Center and New Jersey Medical School-Rutgers, The State University of New Jersey, 225 Warren Street, Newark, NY, 07103, USA. rodrigg2@njms.rutgers.edu.
Rafael Prados-RosalesDepartment of Microbiology and Immunology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Forchheimer Building, Room 411, Bronx, NY, 10461, USA.

Funding

M TUBERCULOSIS SURVIVAL AND GROWTH IN VIVOR01AI044856 · NIAID · UNIV OF MED/DENT OF NJ-NJ MEDICAL SCHOOL · PI RODRIGUEZ, GLORIA MARCELA, SMITH, ISSAR · 1999 to 2014
$6.8M
Mechanisms and regulation of Mycobacterium tuberculosis iron acquisitionR56AI044856 · NIAID · UNIV OF MED/DENT OF NJ-NJ MEDICAL SCHOOL · PI RODRIGUEZ, GLORIA MARCELA, SMITH, ISSAR · 2009 to 2009
$585k
Molecular dissection of vesiculogenesis in Mycobacterium tuberculosisR21AI115091 · NIAID · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI PRADOS-ROSALES, RAFAEL · 2015 to 2016
$459k
NIAID NIH HHS R01 AI044856NIAID NIH HHS R21 AI115091NIAID NIH HHS R56 AI044856
6 · The paper itself

Abstract

The release of cellular factors by means of extracellular vesicles (EVs) is conserved in archaea, bacteria, and eukaryotes. EVs are released by growing bacteria as part of their interaction with their environment and, for pathogenic bacteria, constitute an important component of their interactions with the host. While EVs released by gram-negative bacteria have been extensively studied, the vesicles released by thick cell wall microorganisms like mycobacteria were recognized only recently and are less well understood. Nonetheless, studies of mycobacterial EVs have already suggested roles in pathogenesis, opening exciting new avenues of research aimed at understanding their biogenesis and potential use in antitubercular strategies. In this minireview, we discuss the discovery of mycobacterial vesicles, the current understanding of their nature, content, regulation, and possible functions, as well as their potential therapeutic applications.

Indexed as

Extracellular VesiclesMycobacteriumVirulence FactorsVirulence FactorsIronLipoproteinsMycobacteriumSiderophoresVaccinesVesicles

Identifiers

PMID27020292
PMCPMC4879809

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.