Evidence map›Paper›PMID 27020089›Full record

ArticleBlood2016

Phase IB study of cabozantinib in patients with relapsed and/or refractory multiple myeloma.

Nikoletta Lendvai, Andrew J Yee, Ioanna Tsakos, Aeri Alexander, Sean M Devlin, Hani Hassoun, Neha Korde, Alexander M Lesokhin, Heather Landau, Sham Mailankody and 5 more

Abstract readClinical Trial, Phase ILetterMulticenter Study
In one paragraph

Article in Blood, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Incidence of first and subsequent fractures in multiple myeloma patients: a parallel cohort study using UK CPRD dataset.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026
    Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Nikoletta LendvaiMyeloma Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY; Department of Medicine, Weill Medical College of Cornell University, New York, NY;
Andrew J YeeDivision of Hematology and Oncology, Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA;
Ioanna TsakosMyeloma Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY;
Aeri AlexanderMyeloma Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY;
Sean M DevlinDepartment of Biostatistics and Epidemiology, Memorial Sloan Kettering Cancer Center, New York, NY; and.
Hani HassounMyeloma Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY; Department of Medicine, Weill Medical College of Cornell University, New York, NY;
Neha KordeMyeloma Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY; Department of Medicine, Weill Medical College of Cornell University, New York, NY;
Alexander M LesokhinMyeloma Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY; Department of Medicine, Weill Medical College of Cornell University, New York, NY;
Heather LandauDepartment of Medicine, Weill Medical College of Cornell University, New York, NY; Adult Bone Marrow Transplant Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.
Sham MailankodyMyeloma Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY; Department of Medicine, Weill Medical College of Cornell University, New York, NY;
Guenther KoehneDepartment of Medicine, Weill Medical College of Cornell University, New York, NY; Adult Bone Marrow Transplant Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.
David J ChungDepartment of Medicine, Weill Medical College of Cornell University, New York, NY; Adult Bone Marrow Transplant Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.
Ola LandgrenMyeloma Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY; Department of Medicine, Weill Medical College of Cornell University, New York, NY;
Noopur S RajeDivision of Hematology and Oncology, Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA;
Sergio GiraltDepartment of Medicine, Weill Medical College of Cornell University, New York, NY; Adult Bone Marrow Transplant Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AgedAnilidesFemaleHumansMaleMiddle AgedMultiple MyelomaNeoplasm Recurrence, LocalProtein Kinase InhibitorsPyridinesReceptor Protein-Tyrosine KinasesAnilidescabozantinibProtein Kinase InhibitorsPyridinesReceptor Protein-Tyrosine Kinases

Identifiers

PMID27020089
PMCPMC5003505

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.