Evidence map›Paper›PMID 27019862›Full record

ArticleCurrent opinion in behavioral sciences2016

Perinatal exposure to endocrine disruptors: sex, timing and behavioral endpoints.

Paola Palanza, Susan C Nagel, Stefano Parmigiani, Frederick S Vom Saal

Abstract read
In one paragraph

Article in Current opinion in behavioral sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed.

  1. Review
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  9. From Wingspread to CLARITY: a personal trajectory.Nature reviews. Endocrinology · 2021
    Review
  10. A Review of Recent Studies on Bisphenol A and Phthalate Exposures and Child Neurodevelopment.International journal of environmental research and public health · 2021
    Review
  11. Review
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  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Paola PalanzaUnit of Behavioral Biology, Department of Neuroscience, University of Parma, Viale delle Scienze 11/A, Parma 43100, Italy.
Susan C NagelDepartment of Obstetrics, Gynecology and Women's Health, University of Missouri, Columbia, USA.
Stefano ParmigianiUnit of Behavioral Biology, Department of Neuroscience, University of Parma, Viale delle Scienze 11/A, Parma 43100, Italy.
Frederick S Vom SaalDivision of Biological Sciences, University of Missouri, Columbia, USA.

Funding

Interaction of fetal growth and bisphenol A in obesityR01ES021394 · NIEHS · UNIVERSITY OF MISSOURI-COLUMBIA · PI NAGEL, SUSAN C, VOM SAAL, FREDERICK S · 2012 to 2016
$2.5M
NIEHS NIH HHS R01 ES021394
6 · The paper itself

Abstract

Of the approximately 85,000 chemicals in use, 1000 have been identified as having the ability to disrupt normal endocrine function. Exposure to endocrine disrupting chemicals (EDCs) during critical period in brain differentiation (prenatal and neonatal life) via the mother can alter the course of the development of sexually dimorphic behaviors. Bisphenol A (BPA) is a very high volume chemical used in plastic, resins and other products, and virtually everyone examined has detectable BPA. BPA has estrogenic activity and is one of the most studied EDCs. We review evidence from studies in rodents using dose levels relevant to human exposure. BPA alters behavior and eliminates or in some cases reverses sexually dimorphic behaviors observed in unexposed animals.

Identifiers

PMID27019862
PMCPMC4805122

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.