ArticleResearch ethics2016
Altruistic reasoning in adolescent-parent dyads considering participation in a hypothetical sexual health clinical trial for adolescents.
Article in Research ethics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.
- Experiences and perspectives of children and adolescents participating in pediatric clinical trials: a qualitative evidence synthesis.Archives of public health = Archives belges de sante publique · 2026Pooled it
- Minors' and Young Adults' Experiences of the Research Consent Process in a Phase II Safety Study of Pre-exposure Prophylaxis for HIV.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2017Trial
- Adolescent and Parent Perceptions about Participation in Biomedical Sexual Health Trials.Ethics & human research · 2020Article
- Adolescent-Parent Dyadic Retention in an Interview Study and Changes in Willingness to Participate in a Hypothetical Microbicide Safety Study.Journal of pediatric and adolescent gynecology · 2018Article
- Adolescents' and Parents' Attitudes Toward Adolescent Clinical Trial Participation: Changes Over One Year.Journal of empirical research on human research ethics : JERHRE · 2018Article
- Parents' Perspectives About Adolescent Boys' Involvement in Biomedical HIV Prevention Research.Archives of sexual behavior · 2018Article
- Inclusion of Adolescents in STI/HIV Biomedical Prevention Trials: Autonomy, Decision Making, and Parental Involvement.Clinical practice in pediatric psychology · 2018Article
- Management of Adolescent-Parent Dyads' Discordance for Willingness to Participate in a Reproductive Health Clinical Trial.Journal of empirical research on human research ethics : JERHRE · 2018Article
- Adolescent-Parent Dyad Descriptions of the Decision to Start the HPV Vaccine Series.Journal of pediatric and adolescent gynecology · 2018Article
- What do young people with rheumatic disease believe to be important to research about their condition? A UK-wide study.Pediatric rheumatology online journal · 2017Article
- Adolescent and Parent Willingness to Participate in Microbicide Safety Studies.Journal of pediatric and adolescent gynecology · 2017Article
- Qualitative Analysis of Sexually Experienced Female Adolescents: Attitudes about Vaginal Health.Journal of pediatric and adolescent gynecology · 2016Article
- Parents' and Adolescents' Attitudes about Parental Involvement in Clinical Research.Journal of pediatric and adolescent gynecology · 2016Article
- Adolescents and Their Parents Differ on Descriptions of a Reproductive Health Study.Journal of pediatric and adolescent gynecology · 2016Article
- Moral conflict and competing duties in the initiation of a biomedical HIV prevention trial with minor adolescents.AJOB empirical bioethicsArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 1 country.
Funding
Abstract
Altruism is a well-established reason underlying research participation. Less is known about altruism in adolescent-parent decision-making about clinical trials enrolling healthy adolescents. This qualitative investigation focused on identifying spontaneous statements of altruism within adolescent-parent (dyadic) discussions of participation in a hypothetical phase I clinical trial related to adolescent sexual health. Content analysis revealed several response patterns to each other's altruistic reasoning. Across 70 adolescent-parent dyads in which adolescents were 14-17 years of age and 91% of their parents were mothers, a majority (61%) of dyadic discussions included a statement reflecting altruism. Parents responded to adolescents' statements of altruism more frequently than adolescents responded to parents' statements. Responses included: expresses concern, reiterates altruistic reasoning, agrees with altruistic reasoning, and adds to/expands altruistic reasoning. Since an altruistic perspective was often balanced with concerns about risk or study procedures, researchers cannot assume that altruism will directly lead to study participation. Optimizing the informed consent process for early phase clinical trials involving healthy adolescents may include supporting parents to have conversations with their adolescents which will enhance their capacity to consider all aspects of trial participation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.