Evidence map›Paper›PMID 27019545›Full record

ArticleDrug development research2001

Potent P2X

R Gnana Ravi, Sylvia B Kertesy, George R Dubyak, Kenneth A Jacobson

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Drug development research, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Purine and pyrimidine (P2) receptors as drug targets.Journal of medicinal chemistry · 2002
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 1 country.

R Gnana RaviMolecular Recognition Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes, Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland.
Sylvia B KertesyDepartment of Physiology and Biophysics, Case Western Reserve University School of Medicine, Cleveland, Ohio.
George R DubyakDepartment of Physiology and Biophysics, Case Western Reserve University School of Medicine, Cleveland, Ohio.
Kenneth A JacobsonMolecular Recognition Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes, Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland.
Case Western Reserve University · USNational Institute of Diabetes and Digestive and Kidney Diseases · USNational Institutes of Health · USUniversity School · US

Funding

TRANSMEMBRANE SIGNALLING IN SMOOTH MUSCLE CELL LINESR01GM036387 · NIGMS · CASE WESTERN RESERVE UNIVERSITY · PI DUBYAK, GEORGE R · 1987 to 2014
$4.5M
Development of Drugs Acting at Ion ChannelsZ01DK031127 · NIDDK · NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES · PI JACOBSON, KENNETH ALAN · 2007 to 2008
$385k
Intramural NIH HHS Z01 DK031127Intramural NIH HHS Z99 DK999999NIGMS NIH HHS R01 GM036387
6 · The paper itself

Abstract

Novel analogs of 1-(

Indexed as

ion channelsisoquinolinesKN-62nucleotidespurinesstructure activity relationships

Identifiers

PMID27019545
PMCPMC4807024
OpenAlexW2103028942

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.