ArticleMolecular plant pathology2017
Deep sequencing leads to the identification of eukaryotic translation initiation factor 5A as a key element in Rsv1-mediated lethal systemic hypersensitive response to Soybean mosaic virus infection in soybean.
Article in Molecular plant pathology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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19 citing papers in PubMed, 30 citations in OpenAlex.
- Pangenome-wide insights into eukaryotic translation initiation factors (eIF) genes uncover targets for sterility mosaic disease resistance engineering in pigeonpea.BMC plant biology · 2026Article
- Signaling Pathway Analysis and Downstream Genes Associated with Disease Resistance Mediated byPlants (Basel, Switzerland) · 2026Article
- Genome-Wide Association Study and Genomic Prediction of Soybean Mosaic Virus Resistance.International journal of molecular sciences · 2025Article
- Article
- Comparative transcriptome analysis reveals key pathways and regulatory networks in early resistance ofFrontiers in microbiology · 2023Article
- Characterization of two constitutive promotersaBIOTECH · 2022Article
- A Multi-Level Iterative Bi-Clustering Method for Discovering miRNA Co-regulation Network of Abiotic Stress Tolerance in Soybeans.Frontiers in plant science · 2022Article
- Hypusination, a Metabolic Posttranslational Modification of eIF5A in Plants during Development and Environmental Stress Responses.Plants (Basel, Switzerland) · 2021Review
- Extreme Resistance to Viruses in Potato and Soybean.Frontiers in plant science · 2021Review
- Article
- Virus and Viroid-Derived Small RNAs as Modulators of Host Gene Expression: Molecular Insights Into Pathogenesis.Frontiers in microbiology · 2020Review
- Turnip Mosaic Virus Components Are Released into the Extracellular Space by Vesicles in Infected Leaves.Plant physiology · 2019Article
- Genomics of Plant Disease Resistance in Legumes.Frontiers in plant science · 2019Review
- Dynamin-Like Proteins of Endocytosis in Plants Are Coopted by Potyviruses To Enhance Virus Infection.Journal of virology · 2018Article
- Soybean mosaic virus: a successful potyvirus with a wide distribution but restricted natural host range.Molecular plant pathology · 2018Article
- Exploring the Diversity of Mechanisms Associated With Plant Tolerance to Virus Infection.Frontiers in plant science · 2018Review
- Fine-mapping and identification of a novel locus Rsc15 underlying soybean resistance to Soybean mosaic virus.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2017Article
- Transcriptome Analysis of Capsicum Chlorosis Virus-Induced Hypersensitive Resistance Response in Bell Capsicum.PloS one · 2016Article
- The Current Status of the Soybean-Frontiers in microbiology · 2016Review
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Rsv1, a single dominant resistance locus in soybean, confers extreme resistance to the majority of Soybean mosaic virus (SMV) strains, but is susceptible to the G7 strain. In Rsv1-genotype soybean, G7 infection provokes a lethal systemic hypersensitive response (LSHR), a delayed host defence response. The Rsv1-mediated LSHR signalling pathway remains largely unknown. In this study, we employed a genome-wide investigation to gain an insight into the molecular interplay between SMV G7 and Rsv1-genotype soybean. Small RNA (sRNA), degradome and transcriptome sequencing analyses were used to identify differentially expressed genes (DEGs) and microRNAs (DEMs) in response to G7 infection. A number of DEGs, DEMs and microRNA targets, and the interaction network of DEMs and their target mRNAs responsive to G7 infection, were identified. Knock-down of one of the identified DEGs, the eukaryotic translation initiation factor 5A (eIF5A), diminished the LSHR and enhanced viral accumulation, suggesting the essential role of eIF5A in the G7-induced, Rsv1-mediated LSHR signalling pathway. This work provides an in-depth genome-wide analysis of high-throughput sequencing data, and identifies multiple genes and microRNA signatures that are associated with the Rsv1-mediated LSHR.
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