Evidence map›Paper›PMID 27019375›Full record

ArticleInternational journal of geriatric psychiatry2017

The management of behavioural and psychological symptoms of dementia in the acute general medical hospital: a longitudinal cohort study.

Nicola White, Baptiste Leurent, Kathryn Lord, Sharon Scott, Louise Jones, Elizabeth L Sampson

Abstract read
In one paragraph

Article in International journal of geriatric psychiatry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 4 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nicola WhiteMarie Curie Palliative Care Research Department, Division of Psychiatry, UCL, London, UK.ORCID http://orcid.org/0000-0002-7438-0072
Baptiste LeurentMarie Curie Palliative Care Research Department, Division of Psychiatry, UCL, London, UK.
Kathryn LordMarie Curie Palliative Care Research Department, Division of Psychiatry, UCL, London, UK.
Sharon ScottMarie Curie Palliative Care Research Department, Division of Psychiatry, UCL, London, UK.
Louise JonesMarie Curie Palliative Care Research Department, Division of Psychiatry, UCL, London, UK.
Elizabeth L SampsonMarie Curie Palliative Care Research Department, Division of Psychiatry, UCL, London, UK.

Funding

Marie Curie MCCC-FPR-11-UMarie Curie MCCC-PRO-11-U
6 · The paper itself

Abstract

backgroundThe acute hospital is a challenging place for a person with dementia. Behavioural and psychological symptoms of dementia (BPSD) are common and may be exacerbated by the hospital environment. Concerns have been raised about how BPSD are managed in this setting and about over reliance on neuroleptic medication. This study aimed to investigate how BPSD are managed in UK acute hospitals. METHOD(S): A longitudinal cohort of 230 patients with dementia admitted to two acute NHS hospitals. BPSD were measured every four days (Behave-AD scale), as well as documentation of pharmacological prescriptions and non-pharmacological management.

resultsThe overall prevalence of BPSD was 75%, with aggression and activity disturbance being the most common. Antipsychotics were prescribed for 28 (12%) patients; 70% of these prescriptions were new on admission. Benzodiazepines were prescribed for 27 (12%) patients, antidepressants were prescribed for 37 (16%) patients, and sedatives were prescribed for 14 (3%) patients. Patients who were prescribed antipsychotics, after adjusting for end of life medication, age and dementia severity, were significantly more likely to die (adjusted hazard ratio 5.78, 95% CI 1.57, 21.26, p = 0.008). Non-pharmacological management was used in 55% of participants, most commonly psychosocial interventions (36%) with little evidence of monitoring their effectiveness. A form of restraint was used during 50 (22%) patients' admissions.

conclusionsAntipsychotic medications and psychosocial interventions were the main methods used to manage BPSD; however, these were not implemented or monitored in a systematic fashion.

Indexed as

AggressionAntipsychotic AgentsDementiaAgedCohort StudiesFemaleHospitals, GeneralHumansLongitudinal StudiesMalePrevalenceAntipsychotic Agentsacute hospitalantipsychoticsbehaviourBPSDdementianon-pharmacological management

Identifiers

PMID27019375
PMCPMC5324689

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.