Evidence map›Paper›PMID 27018532›Full record

Trial reportJournal of consulting and clinical psychology2016

Genetics moderate alcohol and intimate partner violence treatment outcomes in a randomized controlled trial of hazardous drinking men in batterer intervention programs: A preliminary investigation.

Gregory L Stuart, John McGeary, Ryan C Shorey, Valerie S Knopik

Open access · hybridAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of consulting and clinical psychology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 4 pooled it
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 syntheses or guidelines pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Gregory L StuartDepartment of Psychology.
John McGearyMental Health and Behavioral Sciences Service.
Ryan C ShoreyDepartment of Psychology, Ohio University.
Valerie S KnopikDepartment of Psychiatry and Human Behavior.
Ohio University · US

Funding

Brief Intervention to Reduce Drinking among BatterersR01AA014193 · NIAAA · BUTLER HOSPITAL (PROVIDENCE, RI) · PI STRONG, DAVID R · 2003 to 2007
$1.7M
A Program of Research and Mentorship on Alcohol Use and Intimate Partner ViolenceK24AA019707 · NIAAA · UNIVERSITY OF TENNESSEE KNOXVILLE · PI STUART, GREGORY L. · 2011 to 2015
$969k
Brown University Shared DNA SequencerS10RR023457 · NCRR · BROWN UNIVERSITY · PI MCGEARY, JOHN E · 2008 to 2008
$147k
NCRR NIH HHS S10 RR023457NIAAA NIH HHS K24 AA019707NIAAA NIH HHS R01 AA014193
6 · The paper itself

Abstract

objectiveWe examined whether a cumulative genetic score (CGS) containing MAOA and 5-HTTLPR polymorphisms moderated drinking and intimate partner violence (IPV) treatment outcomes in hazardous drinking men receiving batterer intervention or batterer intervention plus a brief alcohol intervention.

methodWe conducted a randomized controlled trial with 97 hazardous drinking men who had a relationship partner and were in batterer intervention programs. Participants were randomized to receive 40 hr of standard batterer program (SBP) or the SBP plus a 90-min alcohol intervention (SBP + BAI). Data were collected at baseline, 3-, 6-, and 12-month follow-up, with follow-up rates of 99.0%, 97.9%, and 93.8%, respectively. Genomic DNA was extracted from saliva. Substance use was measured with the timeline followback interview; IPV was assessed with the Revised Conflict Tactics scales. The primary outcomes were drinks per drinking day (DDD), percentage of days abstinent from alcohol (PDA), frequency of physical IPV, and injuries to partners.

resultsConsistent with hypotheses, analyses demonstrated significant treatment condition by CGS interactions for PDA, physical violence, and injuries, but not for DDD. At high levels of the CGS, men in SBP + BAI had greater PDA (B = .16, 95% CI [.04, .27], p = .01), less physical violence perpetration (B = -1.21, 95% CI [-2.21, -.21], p = .02), and fewer injuries to partners (B = -2.37, 95% CI [-3.19, -.82], p = .00) than men in SBP. No differences between the groups in PDA, physical violence, or injuries were observed at low levels of the CGS.

conclusionsFindings demonstrate the potential importance of MAOA and 5-HTTLPR polymorphisms in the treatment of IPV and drinking in men in batterer intervention programs. (PsycINFO Database Record

Indexed as

Outcome Assessment, Health CareAdultAlcohol-Related DisordersBehavior TherapyFemaleHumansMaleMonoamine OxidaseSerotonin Plasma Membrane Transport ProteinsSpouse AbuseMonoamine Oxidasemonoamine oxidase A, humanSerotonin Plasma Membrane Transport ProteinsSLC6A4 protein, human

Identifiers

PMID27018532
PMCPMC4919162
OpenAlexW2324633072

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.