ArticlePharmacognosy magazine
Chemical Discrimination of Cortex Phellodendri amurensis and Cortex Phellodendri chinensis by Multivariate Analysis Approach.
Article in Pharmacognosy magazine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Processed phellodendri Chinensis cortex attenuates diabetic nephropathy via ferroptosis inhibition through GPX4/SLC7A11/Nrf2/HO-1 signaling pathway.Journal of natural medicines · 2026Article
- Rapid identification of chemical profilesFrontiers in pharmacology · 2024Article
- Biological Importance of Phellodendrine in Traditional and Modern Medicines: An Update on Therapeutic Potential in Medicine.Current drug research reviews · 2024Review
- Mechanism underlying the effect of Pulsatilla decoction in hepatocellular carcinoma treatment: a network pharmacology and in vitro analysis.BMC complementary medicine and therapies · 2023Article
- Evaluation of raw and processed Phellodendri Chinensis Cortex using the quality marker analysis strategy by UHPLC-Q-Orbitrap MS and multivariate statistical analysis.Frontiers in chemistry · 2023Article
- Palmatine Protects Against MSU-Induced Gouty Arthritis via Regulating the NF-κB/NLRP3 and Nrf2 Pathways.Drug design, development and therapy · 2022Article
- Untargeted GC-MS-Based Metabolomics for Early Detection of Colorectal Cancer.Frontiers in oncology · 2021Article
- Integrated Strategy FromFrontiers in pharmacology · 2021Article
- Article
- Limonin: A Review of Its Pharmacology, Toxicity, and Pharmacokinetics.Molecules (Basel, Switzerland) · 2019Review
- Exploring the Therapeutic Composition and Mechanism of Jiang-Suan-Chu-Bi Recipe on Gouty Arthritis Using an Integrated Approach Based on Chemical Profile, Network Pharmacology and Experimental Support Using Molecular Cell Biology.Frontiers in pharmacology · 2019Article
- Phellodendri Cortex: A Phytochemical, Pharmacological, and Pharmacokinetic Review.Evidence-based complementary and alternative medicine : eCAM · 2019Review
- Quality Evaluation of Phellodendri Chinensis Cortex by Fingerprint⁻Chemical Pattern Recognition.Molecules (Basel, Switzerland) · 2018Article
- Non-targeted metabolite profiling and specific targeted discrimination strategy for quality evaluation of Cortex Phellodendri from different varieties.RSC advances · 2018Article
- Recent advances and effective strategies in the discovery and applications of natural products.RSC advances · 2018Review
- Efficacy and Safety of the Traditional Japanese Medicine Keigairengyoto in the Treatment of Acne Vulgaris.Dermatology research and practice · 2018Article
- Screening the active compounds of Phellodendri Amurensis cortex for treating prostate cancer by high-throughput chinmedomics.Scientific reports · 2017Article
- Demethyleneberberine alleviates inflammatory bowel disease in mice through regulating NF-κB signaling and T-helper cell homeostasis.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2017Article
- Natural Products Screening for the Identification of Selective Monoamine Oxidase-B Inhibitors.European journal of medicinal plants · 2016Article
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAs herbal medicines have an important position in health care systems worldwide, their current assessment, and quality control are a major bottleneck. Cortex Phellodendri chinensis (CPC) and Cortex Phellodendri amurensis (CPA) are widely used in China, however, how to identify species of CPA and CPC has become urgent. MATERIALS AND
methodsIn this study, multivariate analysis approach was performed to the investigation of chemical discrimination of CPA and CPC.
resultsPrincipal component analysis showed that two herbs could be separated clearly. The chemical markers such as berberine, palmatine, phellodendrine, magnoflorine, obacunone, and obaculactone were identified through the orthogonal partial least squared discriminant analysis, and were identified tentatively by the accurate mass of quadruple-time-of-flight mass spectrometry. A total of 29 components can be used as the chemical markers for discrimination of CPA and CPC. Of them, phellodenrine is significantly higher in CPC than that of CPA, whereas obacunone and obaculactone are significantly higher in CPA than that of CPC.
conclusionThe present study proves that multivariate analysis approach based chemical analysis greatly contributes to the investigation of CPA and CPC, and showed that the identified chemical markers as a whole should be used to discriminate the two herbal medicines, and simultaneously the results also provided chemical information for their quality assessment. SUMMARY: Multivariate analysis approach was performed to the investigate the herbal medicineThe chemical markers were identified through multivariate analysis approachA total of 29 components can be used as the chemical markers. UPLC-Q/TOF-MS-based multivariate analysis method for the herbal medicine samples Abbreviations used: CPC: Cortex Phellodendri chinensis, CPA: Cortex Phellodendri amurensis, PCA: Principal component analysis, OPLS-DA: Orthogonal partial least squares discriminant analysis, BPI: Base peaks ion intensity.
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