Trial reportJournal of pediatric psychology2016
Trajectories of Health-Related Quality of Life Among Children With Newly Diagnosed Epilepsy.
Trial report in Journal of pediatric psychology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Psychological treatments for people with epilepsy.The Cochrane database of systematic reviews · 2017Pooled it
- Supporting treatment adherence regimens in children with epilepsy: A randomized clinical trial.Epilepsia · 2021Trial
- Trajectories of health-related quality of life in youth with chronic physical illness and their siblings.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026Article
- Transdiagnostic Predictors of Health-Related Quality of Life in Children with Autism and Epilepsy: A Cross-Sectional Study.Journal of clinical medicine · 2025Article
- Strong and weak points in the quality of life of school-age children with newly diagnosed uncomplicated epilepsy over the first six months: golden hours for prevention.Croatian medical journal · 2024Article
- Long-term characterization of cognitive phenotypes in children with seizures over 36 months.Epilepsy & behavior : E&B · 2024Article
- Health-related quality of life in children with epilepsy: a concept analysis.Child health nursing research · 2023Article
- Dysfunction of ABC Transporters at the Surface of BBB: Potential Implications in Intractable Epilepsy and Applications of Nanotechnology Enabled Drug Delivery.Current drug metabolism · 2022Review
- Psychometric Properties of the Turkish Version of the Epilepsy Module of the KINDL Quality of Life Scale.Noro psikiyatri arsivi · 2022Article
- Neurobehavioural comorbidities of epilepsy: towards a network-based precision taxonomy.Nature reviews. Neurology · 2021Review
- Behavioral phenotypes of temporal lobe epilepsy.Epilepsia open · 2021Article
- Psychological treatments for people with epilepsy.The Cochrane database of systematic reviews · 2020Review
- Characteristics of Future Models of Integrated Outpatient Care.Healthcare (Basel, Switzerland) · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
objectiveTo identify two-year trajectories of health-related quality of life (HRQOL) among children with newly diagnosed epilepsy, and evaluate key predictors of HRQOL trajectories.
methodsThis study is part of a prospective study of adherence and HRQOL outcomes in children with epilepsy. Caregivers completed an HRQOL questionnaire at one month post diagnosis and every three months thereafter for two years. Chart review and additional questionnaires were used to collect medical variables and seizure outcomes.
resultsParticipants included 120 children with epilepsy and their caregiver. Unique trajectories for overall HRQOL and PedsQL™ subscales were identified and were predominantly stable. A total side effects score emerged as a consistent predictor of all HRQOL domains. Other variables (i.e., socioeconomic status, seizures, internalizing and externalizing problems) uniquely predicted HRQOL domains.
conclusionsMedical and psychosocial interventions should be implemented soon after treatment initiation to target modifiable factors (e.g., side effects, anxiety symptoms), which could improve HRQOL.
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