Evidence map›Paper›PMID 27017941›Full record

ArticleNeuroscience bulletin2016

Smoking and Serum Lipid Profiles in Schizophrenia.

Hui-Mei An, Yun-Long Tan, Shu-Ping Tan, Jing Shi, Zhi-Ren Wang, Fu-De Yang, Xu-Feng Huang, Jair C Soars, Thomas R Kosten, Xiang-Yang Zhang

Open access · bronzeAbstract read
In one paragraph

Article in Neuroscience bulletin, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.2field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 35 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 3 countries.

Hui-Mei AnBeijing HuiLongGuan Hospital, Peking University, Beijing, 100096, China.
Yun-Long TanBeijing HuiLongGuan Hospital, Peking University, Beijing, 100096, China.
Shu-Ping TanBeijing HuiLongGuan Hospital, Peking University, Beijing, 100096, China.
Jing ShiBeijing HuiLongGuan Hospital, Peking University, Beijing, 100096, China.
Zhi-Ren WangBeijing HuiLongGuan Hospital, Peking University, Beijing, 100096, China.
Fu-De YangBeijing HuiLongGuan Hospital, Peking University, Beijing, 100096, China.
Xu-Feng HuangCentre for Translational Neuroscience, School of Medicine, Illawarra Health and Medical Research Institute, University of Wollongong, Wollongong, NSW, Australia.
Jair C SoarsDepartment of Psychiatry and Behavioral Sciences, The University of Texas Health Science Center at Houston, Houston, TX, USA.
Thomas R KostenDepartment of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX, USA. Kosten@bcm.edu.
Xiang-Yang ZhangBeijing HuiLongGuan Hospital, Peking University, Beijing, 100096, China. xiang.y.zhang@uth.tmc.edu.
Peking University · CNBeijing HuiLongGuan Hospital · CNThe University of Texas Health Science Center at Houston · USBaylor College of Medicine · USUniversity of Wollongong · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Schizophrenia is associated with a high prevalence of cigarette-smoking and abnormal lipid profiles. The purpose of this study was to determine whether the profiles differ between schizophrenic smokers and non-smokers and whether the lipid profiles are related to psychopathological symptoms. Serum lipid profiles were measured in 130 male inpatients with DSM-IV-defined schizophrenia: 104 smokers and 26 non-smokers. Symptoms were assessed using the Positive and Negative Syndrome Scale (PANSS). Our results showed that positive PANSS symptoms were fewer in smokers than in non-smokers, while the negative symptoms were fewer in those who smoked more cigarettes. Total protein and globulin levels were significantly lower in the smokers than in the non-smokers. However, there was no significant difference in total cholesterol, triglycerides, high-density lipoprotein cholesterol (HDL-c), low-density lipoprotein cholesterol, apolipoprotein A1, or apolipoprotein B between the smokers and non-smokers. However, the PANSS positive subscale had a significant negative correlation with the HDL-c levels (a protective factor) in the smokers but not in the non-smokers. Our findings suggest that schizophrenic patients who smoke have fewer psychotic symptoms, but contrary to expectation, smoking does not alter lipid profile levels.

Indexed as

Schizophrenic PsychologyAdultAgedAnalysis of VarianceHumansLipidsMaleMiddle AgedPsychiatric Status Rating ScalesSchizophreniaSmokingLipidsCigarette smokingLipid profilesNicotineSchizophreniaSymptoms

Identifiers

PMID27017941
PMCPMC5563778
OpenAlexW2312730196

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.