ReviewAuris, nasus, larynx2016
Cervical lymph node metastasis in adenoid cystic carcinoma of oral cavity and oropharynx: A collective international review.
Review in Auris, nasus, larynx, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
14 citing papers in PubMed, 45 citations in OpenAlex.
- Distribution of Sentinel Nodes in Non-Parotid Salivary Gland Tumors-A Feasibility Study.Cancer reports (Hoboken, N.J.) · 2026Observational
- Molecular Profiling of Sinonasal Adenoid Cystic Carcinoma: Canonical and Noncanonical Gene Fusions and Mutation.The American journal of surgical pathology · 2025Article
- [Misdiagnosis of adenoid cystic carcinoma of oropharynx: a case report].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2023Article
- Occult Neck Metastases in Head and Neck Adenoid Cystic Carcinoma: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2022Review
- Occult neck metastases risk factors and the role of elective neck dissection in cT3-4N0 adenoid cystic carcinoma of the parotid gland.Frontiers in oncology · 2022Article
- Adenoid cystic carcinoma. An indolent but aggressive tumour. Part B: treatment and prognosis.Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale · 2021Review
- Primary Intraosseous Adenoid Cystic Carcinoma with Widespread Skeletal Metastases Showing Features of High-Grade Transformation.Head and neck pathology · 2021Article
- CCL27 Signaling in the Tumor Microenvironment.Advances in experimental medicine and biology · 2021Review
- Article
- [Cervical lymph node metastasis in adenoid cystic carcinoma of the salivary glands: A clinicopathologic study].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2020Article
- Predictors of Outcome in Adenoid Cystic Carcinoma of Salivary Glands: A Clinicopathologic Study With Correlation Between MYB Fusion and Protein Expression.The American journal of surgical pathology · 2017Article
- Article
- Evaluation of metastasis and 5-year survival in oral squamous cell carcinoma patients in Isfahan (2001-2015).Dental research journalArticle
- Adenoid cystic carcinoma of palatine tonsil: A case report.Science progressArticle
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Authors and funding
32 authors at 20 institutions in 11 countries.
Funding
Abstract
The purpose of this study was to suggest general guidelines in the management of the N0 neck of oral cavity and oropharyngeal adenoid cystic carcinoma (AdCC) in order to improve the survival of these patients and/or reduce the risk of neck recurrences. The incidence of cervical node metastasis at diagnosis of head and neck AdCC is variable, and ranges between 3% and 16%. Metastasis to the cervical lymph nodes of intraoral and oropharyngeal AdCC varies from 2% to 43%, with the lower rates pertaining to palatal AdCC and the higher rates to base of the tongue. Neck node recurrence may happen after treatment in 0-14% of AdCC, is highly dependent on the extent of the treatment and is very rare in patients who have been treated with therapeutic or elective neck dissections, or elective neck irradiation. Lymph node involvement with or without extracapsular extension in AdCC has been shown in most reports to be independently associated with decreased overall and cause-specific survival, probably because lymph node involvement is a risk factor for subsequent distant metastasis. The overall rate of occult neck metastasis in patients with head and neck AdCC ranges from 15% to 44%, but occult neck metastasis from oral cavity and/or oropharynx seems to occur more frequently than from other locations, such as the sinonasal tract and major salivary glands. Nevertheless, the benefit of elective neck dissection (END) in AdCC is not comparable to that of squamous cell carcinoma, because the main cause of failure is not related to neck or local recurrence, but rather, to distant failure. Therefore, END should be considered in patients with a cN0 neck with AdCC in some high risk oral and oropharyngeal locations when postoperative RT is not planned, or the rare AdCC-high grade transformation.
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