Evidence map›Paper›PMID 27017136›Full record

ReviewAcademic radiology2016

How Can Advanced Imaging Be Used to Mitigate Potential Breast Cancer Overdiagnosis?

Habib Rahbar, Elizabeth S McDonald, Janie M Lee, Savannah C Partridge, Christoph I Lee

Abstract readReview
In one paragraph

Review in Academic radiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Overdetection of Breast Cancer.Current oncology (Toronto, Ont.) · 2022
    Article
  3. Article
  4. Optimal Screening in Breast Cancer Survivors With Dense Breasts on Mammography.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2020
    Article
  5. Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. The mammography debate: the senior years.Current oncology (Toronto, Ont.) · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Habib RahbarDepartment of Radiology, University of Washington School of Medicine, 825 Eastlake Avenue East, G3-200, Seattle, WA 98109-1023.
Elizabeth S McDonaldDepartment of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania 19104-4283; Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104-4283.
Janie M LeeDepartment of Radiology, University of Washington School of Medicine, 825 Eastlake Avenue East, G3-200, Seattle, WA 98109-1023; Hutchinson Institute for Cancer Outcomes Research, Seattle, Washington 98109-1023.
Savannah C PartridgeDepartment of Radiology, University of Washington School of Medicine, 825 Eastlake Avenue East, G3-200, Seattle, WA 98109-1023.
Christoph I LeeDepartment of Radiology, University of Washington School of Medicine, 825 Eastlake Avenue East, G3-200, Seattle, WA 98109-1023; Department of Health Services, University of Washington School of Public Health, Seattle, Washington 98109-1023; Hutchinson Institute for Cancer Outcomes Research, Seattle, Washington 98109-1023. Electronic address: stophlee@uw.edu.

Funding

Institutional Clinical and Translational Science AwardUL1TR000003 · NCATS · UNIVERSITY OF PENNSYLVANIA · PI FITZGERALD, GARRET A · 2012 to 2015
$38.9M
Targeted immunotherapy of breast cancer with central memory T cellsP50CA138293 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI PORTER, PEGGY L. · 2010 to 2014
$11.0M
MR Diffusion Tensor Imaging for Detection and Characterization of Breast LesionsR01CA151326 · NCI · UNIVERSITY OF WASHINGTON · PI PARTRIDGE, SAVANNAH CORRINA · 2010 to 2014
$1.3M
NCATS NIH HHS UL1 TR000003NCI NIH HHS P50 CA138293NCI NIH HHS R01 CA151326
6 · The paper itself

Abstract

Radiologists, as administrators and interpreters of screening mammography, are considered by some to be major contributors to the potential harms of screening, including overdiagnosis and overtreatment. In this article, we outline current efforts within the breast imaging community toward mitigating screening harms, including the widespread adoption of tomosynthesis and potentially adjusting screening frequency and thresholds for image-guided breast biopsy. However, the emerging field of breast radiomics may offer the greatest promise for reducing overdiagnosis by identifying imaging-based biomarkers strongly associated with tumor biology, and therefore helping prevent the harms of unnecessary treatment for indolent cancers.

Indexed as

MammographyMedical OveruseBiomarkersBreastBreast NeoplasmsEarly Detection of CancerFemaleHumansImage Interpretation, Computer-AssistedMass ScreeningBiomarkersbreast cancerbreast imagingOverdiagnosisscreening risks

Identifiers

PMID27017136
PMCPMC4867276

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.