ArticleBrain : a journal of neurology2016
Both mitochondrial DNA and mitonuclear gene mutations cause hearing loss through cochlear dysfunction.
Article in Brain : a journal of neurology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 22 citations in OpenAlex.
- Is auditory neuropathy an appropriate term? A systematic literature review on its aetiology and pathogenesis.Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale · 2021Pooled it
- Hearing impairment in MELAS: new prospective in clinical use of microRNA, a systematic review.Orphanet journal of rare diseases · 2018Pooled it
- Clinical characteristics and hearing impairment in carriers of the m.3243 A > G variant.Journal of human genetics · 2026Article
- Ischemic Stroke After Cochlear Implantation in a Patient With an Undiagnosed Mitochondrial Disorder.Cureus · 2025Article
- Beyond the cochlea: exploring the multifaceted nature of hearing loss in primary mitochondrial diseases.Brain communications · 2024Article
- Auditory and vestibular function in mitochondrial patients harbouring the m.3243A>G variant.Brain communications · 2024Article
- Red Flags in Primary Mitochondrial Diseases: What Should We Recognize?International journal of molecular sciences · 2023Review
- Hearing Impairment and Neuroimaging Results in Mitochondrial Diseases.Journal of personalized medicine · 2023Article
- Pathogenic mtDNA variants, in particular single large-scale mtDNA deletions, are strongly associated with post-lingual onset sensorineural hearing loss in primary mitochondrial disease.Molecular genetics and metabolism · 2022Article
- Anatomic & metabolic brain markers of the m.3243A>G mutation: A multi-parametric 7T MRI study.NeuroImage. Clinical · 2018Article
- Patient care standards for primary mitochondrial disease: a consensus statement from the Mitochondrial Medicine Society.Genetics in medicine : official journal of the American College of Medical Genetics · 2017Review
- Screening for Maternally Inherited Diabetes and Deafness in Large Cohorts of Hearing Impaired and Diabetic Patients.Ear and hearingArticle
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Authors and funding
12 authors at 6 institutions in 1 country.
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Abstract
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.