Evidence map›Paper›PMID 27016318›Full record

ArticleJournal of neurointerventional surgery2017

Experimental evaluation of stent retrievers' mechanical properties and effectiveness.

Paolo Machi, Franck Jourdan, Dominique Ambard, Cedric Reynaud, Kyriakos Lobotesis, Mathieu Sanchez, Alain Bonafé, Vincent Costalat

Open access · hybridAbstract readEvaluation Study
In one paragraph

Article in Journal of neurointerventional surgery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 79 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
79citing papers in PubMed, 3 pooled it
10.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

79 citing papers in PubMed, 3 syntheses or guidelines pooled it, 164 citations in OpenAlex.

  1. Pooled it
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  10. A novel method for preparing clot analogs under dynamic vortical flow for testing mechanical thrombectomy devices.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
    Article
  11. Potential of Guidewire-Clot Interaction Forces for Clot Detection in Robotic Mechanical Thrombectomy.The international journal of medical robotics + computer assisted surgery : MRCAS · 2025
    Article
  12. The use of the NeVa stent-retriever for bail-out mechanical thrombectomy.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
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  15. Early results with EmboTrap III stent retriever: A multicenter US experience.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
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19 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Paolo MachiCentre Hospitalier Universitaire Gui de Chauliac, Montpellier, France.
Franck JourdanDepartment of Mechanical Engineering, University of Montpellier, France.
Dominique AmbardDepartment of Mechanical Engineering, University of Montpellier, France.
Cedric ReynaudDepartment of Mechanical Engineering, University of Montpellier, France.
Kyriakos LobotesisImperial College Healthcare NHS, London, UK.
Mathieu SanchezDepartment of Mechanical Engineering, University of Montpellier, France.
Alain BonaféCentre Hospitalier Universitaire Gui de Chauliac, Montpellier, France.
Vincent CostalatCentre Hospitalier Universitaire Gui de Chauliac, Montpellier, France.
Hôpital Saint Eloi · FRLaboratoire de Mécanique et Génie Civil · FRUniversité de Montpellier · FRHôpital Gui de Chauliac · FRImperial College Healthcare NHS Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFive randomized controlled trials recently appeared in the literature demonstrating that early mechanical thrombectomy in patients with acute ischemic stroke is significantly related to an improved outcome. Stent retrievers are accepted as the most effective devices for intracranial thrombectomy.

objectiveTo analyze the mechanical properties of stent retrievers, their behavior during retrieval, and interaction with different clots and to identify device features that might correlate with the effectiveness of thrombus removal. MATERIALS AND

methodsAll stent retrievers available in France up to June 2015 were evaluated by mechanical and functional tests aimed at investigating the variation of their radial force and their behavior during retrieval. Devices were also tested during in vitro thrombectomies using white and red experimental thrombi produced with human blood. Functional tests and in vitro thrombectomies were conducted using a rigid 3D printed vascular model.

resultsMechanical tests showed a variation in radial force during retrieval for each stent. A constant radial force during retrieval was related to continuous cohesion over the vessel wall and a higher rate of clot removal efficacy. All stent retrievers failed when interacting with white large thrombi (diameter ≥6 mm).

conclusionsNone of the tested devices were effective in removing white clots of large diameter (≥6 mm). Constant radial force during retrieval allows constant cohesion to the vessel wall and pressure over the clot; such features allow for a higher rate of clot removal.

Indexed as

Biomechanical PhenomenaDevice RemovalHumansMaterials TestingStentsStrokeThrombectomyThrombosisTreatment OutcomeStentStrokeThrombectomy

Identifiers

PMID27016318
PMCPMC5339553
OpenAlexW2303784857

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.