Evidence map›Paper›PMID 27016264›Full record

ArticleHeadache2016

Association of Migraine Headaches With Suicidal Ideation Among Pregnant Women in Lima, Peru.

Lauren E Friedman, Bizu Gelaye, Marta B Rondon, Sixto E Sanchez, B Lee Peterlin, Michelle A Williams

Open access · bronzeAbstract read
In one paragraph

Article in Headache, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 4 pooled it
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 4 syntheses or guidelines pooled it, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Lauren E FriedmanHarvard T. H. Chan School of Public Health - Epidemiology, Boston, MA, USA.
Bizu GelayeHarvard T. H. Chan School of Public Health - Epidemiology, Boston, MA, USA.
Marta B RondonCayetano Heredia Peruvian University - Department of Medicine, Lima, Peru.
Sixto E SanchezAsociación Civil Proyectos en Salud, Lima, Peru.
B Lee PeterlinJohns Hopkins School of Medicine - Neurology, Baltimore, MD, USA.
Michelle A WilliamsHarvard T. H. Chan School of Public Health - Epidemiology, Boston, MA, USA.
Harvard University · USJohns Hopkins University · USPeruvian University of Applied Sciences · PEUniversidad Peruana Cayetano Heredia · PE

Funding

University of Washington MHIRT Training Program GrantT37MD001449 · NIMHD · UNIVERSITY OF WASHINGTON · PI WILLIAMS, MICHELLE A. · 2005 to 2018
$3.5M
A Cohort Study of Preterm Delivery in Relation to Partner Abuse, Mood and AnxietyR01HD059835 · NICHD · UNIVERSITY OF WASHINGTON · PI WILLIAMS, MICHELLE A. · 2010 to 2014
$2.8M
Impact and Mechansims of Migraine Comorbidites on Migraine Onset and ProgressionK23NS078345 · NINDS · JOHNS HOPKINS UNIVERSITY · PI PETERLIN, BARBARA LEE · 2012 to 2016
$888k
NICHD NIH HHS R01 HD059835NICHD NIH HHS R01-HD-059835NIMHD NIH HHS T37 MD001449NIMHD NIH HHS T37-MD-001449NINDS NIH HHS K23 NS078345
6 · The paper itself

Abstract

backgroundSuicide is a leading cause of maternal death globally, and suicide prevalence rates have been shown to be increased in those with migraine. No previous study has examined the association between migraine and suicidal ideation during pregnancy.

objectiveTo examine the association between migraine and suicidal ideation among a cohort of pregnant women.

methodsA cross-sectional study was conducted among 3372 pregnant women attending prenatal care clinics in Lima, Peru. Suicidal ideation and depression were assessed using the Patient Health Questionnaire-9 (PHQ-9) scale during early pregnancy. Migraine classification (including migraine and probable migraine) was based on International Classification of Headache Disorders-III beta criteria. Multivariable logistic regression analyses were performed to estimate odds ratios (OR) and 95% confidence intervals (95% CI).

resultsSuicidal ideation was more common among those with migraine (25.6%) as compared to those with probable migraine (22.1%, P < .001) or non-migraineurs (12.3%, P < .001). After adjusting for confounders, including depression, those with migraine or probable migraine had a 78% increased odds of suicidal ideation (OR = 1.78; 95% CI: 1.46-2.17), as compared with non-migraineurs. Women with both migraine and depression had a 4.14-fold increased odds of suicidal ideation (OR = 4.14; 95% CI: 3.17-5.42) compared to those with neither condition.

conclusionMigraine is associated with increased odds of suicidal ideation in pregnant women even when controlling for depression. These findings support the consideration of screening women with comorbid migraine and depression for suicidal behavior during pregnancy.

Indexed as

Suicidal IdeationAdolescentAdultCross-Sectional StudiesDepressionFemaleHumansMigraine DisordersPeruPregnancyPregnancy ComplicationsSurveys and QuestionnairesYoung Adultdepressionmigrainepregnancysuicidal ideation

Identifiers

PMID27016264
PMCPMC4837000
OpenAlexW2306497362

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.