ArticleTAG. Theoretical and applied genetics. Theoretische und angewandte Genetik2016
A fragment substitution in the promoter of CsHDZIV11/CsGL3 is responsible for fruit spine density in cucumber (Cucumis sativus L.).
Article in TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- A Novel AP2/ERF Transcription Factor Controls Trichome Initiation and Fruit Development in Cucumber.Plant biotechnology journal · 2026Article
- The role, regulation and application of plant fruit trichomes.Molecular horticulture · 2025Review
- Mutations in a Leucine-Rich Repeat Receptor-Like Kinase gene result in male sterility and reduction in the number and size of fruit warts in cucumber (Cucumis sativus L.).TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2024Article
- Article
- QTL mapping and stability analysis of trichome density in zucchini (Frontiers in plant science · 2023Article
- Morphological and Genetic Diversity of Cucumber (Plants (Basel, Switzerland) · 2022Review
- Ectopic Expression ofInternational journal of molecular sciences · 2022Article
- Serial-Omics and Molecular Function Study Provide Novel Insight into Cucumber Variety Improvement.Plants (Basel, Switzerland) · 2022Review
- Graph-based pan-genome reveals structural and sequence variations related to agronomic traits and domestication in cucumber.Nature communications · 2022Article
- Molecular Mechanisms of Plant Trichome Development.Frontiers in plant science · 2022Review
- HECATE2 acts with GLABROUS3 and Tu to boost cytokinin biosynthesis and regulate cucumber fruit wart formation.Plant physiology · 2021Article
- Molecular research progress and improvement approach of fruit quality traits in cucumber.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2021Review
- Article
- A SNP of HD-ZIP I transcription factor leads to distortion of trichome morphology in cucumber (Cucumis sativus L.).BMC plant biology · 2021Article
- Molecularly tagged genes and quantitative trait loci in cucumber with recommendations for QTL nomenclature.Horticulture research · 2020Review
- Perspectives of CRISPR/Cas-mediatedHorticulture research · 2020Review
- Classification of fruit trichomes in cucumber and effects of plant hormones on type II fruit trichome development.Planta · 2019Article
- CsMYB60 is a key regulator of flavonols and proanthocyanidans that determine the colour of fruit spines in cucumber.Journal of experimental botany · 2019Article
- Novel loci fsd6.1 and Csgl3 regulate ultra-high fruit spine density in cucumber.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2019Article
- Combined fine mapping, genetic diversity, and transcriptome profiling reveals that the auxin transporter gene ns plays an important role in cucumber fruit spine development.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2018Article
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9 authors.
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No grant is acknowledged in the PubMed record.
Abstract
key messageThe indel in the promoter of CsHDZIV11 co-segregates with fruit spine density and could be used for molecular breeding in cucumber. Fruit spine density is an important quality trait for marketing in cucumber (Cucumis sativus L.). However, the molecular basis of fruit spine density in cucumber remains unclear. In this study, we isolated a mutant, few spines 1 (fs1), from CNS2 (wild type, WT), a North China-type cucumber with a high density of fruit spines. Genetic analysis showed that fs1 was controlled by a single recessive Mendelian factor. Bulked segregant analysis combined with genome resequencing were used for mapping fs1 in the F2 population derived from a cross between the fs1 mutant and WT, and it was located on chromosome 6 through association analysis. To develop more polymorphic markers to locate fs1, another F2 population was constructed from the cross between fs1 and 'Chinese long' 9930. Then, fs1 was narrowed down to a 110.4-kb genomic region containing 25 annotated genes. A fragment substitution was identified in the promoter region of Csa6M514870 between fs1 and WT. This fragment in fs1 was also present in wild cucumber. Csa6M514870 encodes a PDF2-related protein, a homeodomain-leucine zipper IV transcription factor (CsHDZIV11/CsGL3) sharing high identity and similarity with proteins related to trichome formation or epidermal cell differentiation. Quantitative reverse-transcription PCR revealed a higher expression level of CsHDZIV11 in young fruits from fs1 compared to WT. A molecular marker based on this indel co-segregated with the spine density. This work provides a solid foundation not only for understanding the molecular mechanism of fruit spine density, but also for molecular breeding in cucumber.
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