Evidence map›Paper›PMID 27015458›Full record

ArticleThe Journal of investigative dermatology2016

Autoantibodies to Collagen XVII Are Present in Parkinson's Disease and Localize to Tyrosine-Hydroxylase Positive Neurons.

Kelly A N Messingham, Samantha Aust, Joseph Helfenberger, Krystal L Parker, Susan Schultz, Julie McKillip, Nandakumar S Narayanan, Janet A Fairley

Open access · bronzeAbstract readComparative StudyLetter
In one paragraph

Article in The Journal of investigative dermatology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Bullous pemphigoid burden of disease, management and unmet therapeutic needs.Journal of the European Academy of Dermatology and Venereology : JEADV · 2025
    Review
  4. Review
  5. Coexistence of Pemphigus Foliaceus and Bullous Pemphigoid: A Case Report.Clinical, cosmetic and investigational dermatology · 2024
    Article
  6. Review
  7. Article
  8. BP180/Collagen XVII: A Molecular View.International journal of molecular sciences · 2021
    Review
  9. Article
  10. The Relationship Between Alzheimer's Disease and Skin Diseases: A Review.Clinical, cosmetic and investigational dermatology · 2021
    Review
  11. Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Kelly A N MessinghamDepartment of Dermatology, University of Iowa, Iowa City, IA.
Samantha AustDepartment of Dermatology, University of Iowa, Iowa City, IA.
Joseph HelfenbergerDepartment of Dermatology, University of Iowa, Iowa City, IA.
Krystal L ParkerDepartment of Neurology and Aging Mind and Brain Initiative, University of Iowa, Iowa City, IA.
Susan SchultzDepartment of Psychiatry, Carver College of Medicine, University of Iowa, Iowa City, IA.
Julie McKillipDepartment of Dermatology, University of Iowa, Iowa City, IA.
Nandakumar S NarayananDepartment of Neurology and Aging Mind and Brain Initiative, University of Iowa, Iowa City, IA.
Janet A FairleyDepartment of Dermatology, University of Iowa, Iowa City, IA; Veterans Administration Medical Center, Iowa City, IA. Electronic address: janet-fairley@uiowa.edu.
University of Iowa · US

Funding

University of Iowa Clinical and Translational Science ProgramUL1TR000442 · NCATS · UNIVERSITY OF IOWA · PI ROSENTHAL, GARY E · 2012 to 2013
$10.0M
The University of Iowa Clinical and Translational Science AwardU54TR001356 · NCATS · UNIVERSITY OF IOWA · PI WINOKUR, PATRICIA · 2015 to 2016
$7.1M
SHORT-TERM TRAINING: STUDENTS IN HEALTH PROF. SCHOOLST35HL007485 · NHLBI · UNIVERSITY OF IOWA · PI ROGHAIR, ROBERT D · 1985 to 2019
$4.3M
Prefrontal dopamine and cognitive symptoms of Parkinsons diseaseK08NS078100 · NINDS · YALE UNIVERSITY · PI NARAYANAN, NANDAKUMAR · 2012 to 2016
$908k
TRAINING IN THE HEALTH PROFESSIONST35HL007584 · NHLBI · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI PAVALKO, FREDRICK M · 1985 to 2005
$865k
Insulin Resistance and Vascular Complications in Obesity and Type 2 DiabetesI01BX001680 · VA · IOWA CITY VA MEDICAL CENTER · PI YOREK, MARK A. · 2012 to 2015
–
The Role of IgE in Autoimmune Skin DiseasesI01CX000317 · VA · IOWA CITY VA MEDICAL CENTER · PI FAIRLEY, JANET A · 2011 to 2013
–
BLRD VA I01 BX001680CSRD VA I01 CX000317NCATS NIH HHS 2UL1 TR000442-06NCATS NIH HHS U54 TR001356NCATS NIH HHS UL1 TR000442NHLBI NIH HHS T35 HL007485NHLBI NIH HHS T35 HL007584NINDS NIH HHS K08 NS078100
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AutoantibodiesAutoantigensBiomarkersCase-Control StudiesCollagen Type XVIIConfidence IntervalsFemaleFluorescent Antibody Technique, IndirectHumansMaleNeuronsNon-Fibrillar CollagensParkinson DiseasePemphigoid, BullousReference ValuesTyrosine 3-MonooxygenaseAutoantibodiesAutoantigensBiomarkersCollagen Type XVIINon-Fibrillar CollagensTyrosine 3-Monooxygenase

Identifiers

PMID27015458
PMCPMC4809024
OpenAlexW2234912438

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.