Evidence map›Paper›PMID 27015386›Full record

ReviewMedicine and science in sports and exercise2016

Translating Fatigue to Human Performance.

Roger M Enoka, Jacques Duchateau

2 registry-linked trialsAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Medicine and science in sports and exercise, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 408 papers, 14 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
408citing papers in PubMed, 14 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03153033 completednot on this mapstarted 2017, after this paper: background citation

The Effect of a Wheelchair Propulsion-induced Fatigue Protocol on Biomechanical and Neuromuscular Risk Factors of Shoulder Pain in Persons With a Spinal Cord Injury Living in Switzerland: a Cross-sectional Study With a Repeated Measures Within Subject Design

TypeobservationalSponsorSwiss Paraplegic Research, NottwilRan2017 to 2018Enrolled50ConditionsSpinal Cord Injuries, Fatigue, Muscle, HeartArmsFatigue protocol
NCT03644329 naunknown statusnot on this mapstarted 2018, after this paper: background citation

Effect of Resistance Training Variable Manipulation (Intensity and Volume) on Body Composition, Fatigability and Functional Capacity in Postmenopausal Breast Cancer Survivors.

TypeinterventionalSponsorUniversidade Federal do Triangulo MineiroRan2018 to 2019Enrolled80ConditionsBreast Cancer Survivors, PostmenopauseArmsControl group, Lower-load resistance training (LL), Higher-load resistance training (HL), Higher-volume resistance training (HV)
3 · Its place in the literature

Who cites it

408 citing papers in PubMed, 14 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Effects of exercise on muscle fatigability in COPD: a systematic review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2025
    Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Pooled it
  9. Pooled it
  10. Pooled it
  11. Pooled it
  12. Occupation-Induced Fatigue and Impacts on Emergency First Responders: A Systematic Review.International journal of environmental research and public health · 2023
    Pooled it
  13. Pooled it
  14. Pooled it
  15. Trial
  16. Trial
  17. Trial
  18. Trial
  19. Trial
  20. Trial

348 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Roger M Enoka1Department of Integrative Physiology, University of Colorado, Boulder, CO; and 2Laboratory of Applied Biology and Neurophysiology, ULB Neuroscience Institute, Université Libre de Bruxelles (ULB), Bruxelles, BELGIUM.
Jacques Duchateau

Funding

Neuromuscular Electrical Stimulation and Mobility in Multiple SclerosisR03HD079508 · NICHD · UNIVERSITY OF COLORADO · PI ENOKA, ROGER M. · 2014 to 2015
$154k
NICHD NIH HHS R03 HD079508
6 · The paper itself

Abstract

Despite flourishing interest in the topic of fatigue-as indicated by the many presentations on fatigue at the 2015 Annual Meeting of the American College of Sports Medicine-surprisingly little is known about its effect on human performance. There are two main reasons for this dilemma: 1) the inability of current terminology to accommodate the scope of the conditions ascribed to fatigue, and 2) a paucity of validated experimental models. In contrast to current practice, a case is made for a unified definition of fatigue to facilitate its management in health and disease. On the basis of the classic two-domain concept of Mosso, fatigue is defined as a disabling symptom in which physical and cognitive function is limited by interactions between performance fatigability and perceived fatigability. As a symptom, fatigue can only be measured by self-report, quantified as either a trait characteristic or a state variable. One consequence of such a definition is that the word fatigue should not be preceded by an adjective (e.g., central, mental, muscle, peripheral, and supraspinal) to suggest the locus of the changes responsible for an observed level of fatigue. Rather, mechanistic studies should be performed with validated experimental models to identify the changes responsible for the reported fatigue. As indicated by three examples (walking endurance in old adults, time trials by endurance athletes, and fatigue in persons with multiple sclerosis) discussed in the review, however, it has proven challenging to develop valid experimental models of fatigue. The proposed framework provides a foundation to address the many gaps in knowledge of how laboratory measures of fatigue and fatigability affect real-world performance.

Indexed as

AgingFatigueHumansMultiple SclerosisMuscle FatiguePerceptionPhysical EnduranceSportsTerminology as TopicWalking

Identifiers

PMID27015386
PMCPMC5035715

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.