ReviewMedicine and science in sports and exercise2016
The Relevance of Sex Differences in Performance Fatigability.
Review in Medicine and science in sports and exercise, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 135 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
135 citing papers in PubMed, 6 syntheses or guidelines pooled it, 276 citations in OpenAlex.
- Sex differences in human skeletal muscle fiber types and the influence of age, physical activity, and muscle group: A systematic review and meta-analysis.Physiological reports · 2025Pooled it
- Pooled it
- The Role of Biomarkers in Monitoring Chronic Fatigue Among Male Professional Team Athletes: A Systematic Review.Sensors (Basel, Switzerland) · 2024Pooled it
- Concurrent Strength and Endurance Training: A Systematic Review and Meta-Analysis on the Impact of Sex and Training Status.Sports medicine (Auckland, N.Z.) · 2024Pooled it
- Pooled it
- The Acute Neuromuscular Responses to Cluster Set Resistance Training: A Systematic Review and Meta-Analysis.Sports medicine (Auckland, N.Z.) · 2019Pooled it
- Acute Responses and Chronic Adaptations to Cluster Versus Traditional Set Resistance Training in Males and Females.European journal of sport science · 2026Trial
- Biological sex as a tailoring variable for exercise prescription in hospitalized older adults.The journal of nutrition, health & aging · 2024Trial
- Acute Effects of Complex Conditioning Activities on Athletic Performance and Achilles Tendon Stiffness in Male Basketball Players.Journal of sports science & medicine · 2023Trial
- Gender benefit in laparoscopic surgical performance using a 3D-display system: data from a randomized cross-over trial.Surgical endoscopy · 2022Trial
- The gender dependent influence of sodium bicarbonate supplementation on anaerobic power and specific performance in female and male wrestlers.Scientific reports · 2020Trial
- Ischemic preconditioning has no effect on maximal arm cycling exercise in women.European journal of applied physiology · 2020Trial
- Sex-Based Differences in Anthropometric Profiles and Physiological Responses to High-Intensity Strength-Endurance Exercise in Paramedic Students: A Cross-Sectional Study.Journal of functional morphology and kinesiology · 2026Article
- Sex differences in climbing endurance emerge from combined physiological adaptation and neural strategies.European journal of applied physiology · 2026Article
- Fatigue-induced changes in VMO-VL EMG correlation in individuals with patellofemoral pain.European journal of applied physiology · 2026Article
- Physiological Basis of Sex Differences in Human Performance and Exercise-Associated Pathology.Clinical endocrinology · 2026Review
- Changes in physical performance with aging in master athletes and in the general population: an update.European journal of translational myology · 2026Article
- Can Changes in Sit-To-Stand Performance Throughout A 30-S Time Interval Be Used as A Marker of Performance Fatigability in Middle-Aged To Older Adults?Journal of sports science & medicine · 2026Article
- Highly Trained Female Runners Show Greater Durability and Physiological Resilience Than Performance-Matched Male Counterparts.Scandinavian journal of medicine & science in sports · 2026Article
- The interactive effects of biological sex and skeletal muscle fiber properties on knee-extensor muscle relaxation induced by TMS in unfatigued and fatigued states.European journal of applied physiology · 2026Article
75 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
Performance fatigability differs between men and women for a range of fatiguing tasks. Women are usually less fatigable than men, and this is most widely described for isometric fatiguing contractions and some dynamic tasks. The sex difference in fatigability is specific to the task demands so that one mechanism is not universal, including any sex differences in skeletal muscle physiology, muscle perfusion, and voluntary activation. However, there are substantial knowledge gaps about the task dependency of the sex differences in fatigability, the involved mechanisms, and the relevance to clinical populations and with advanced age. The knowledge gaps are in part due to the significant deficits in the number of women included in performance fatigability studies despite a gradual increase in the inclusion of women for the last 20 yr. Therefore, this review 1) provides a rationale for the limited knowledge about sex differences in performance fatigability, 2) summarizes the current knowledge on sex differences in fatigability and the potential mechanisms across a range of tasks, 3) highlights emerging areas of opportunity in clinical populations, and 4) suggests strategies to close the knowledge gap and understanding the relevance of sex differences in performance fatigability. The limited understanding about sex differences in fatigability in healthy and clinical populations presents as a field ripe with opportunity for high-impact studies. Such studies will inform on the limitations of men and women during athletic endeavors, ergonomic tasks, and daily activities. Because fatigability is required for effective neuromuscular adaptation, sex differences in fatigability studies will also inform on optimal strategies for training and rehabilitation in both men and women.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.