Evidence map›Paper›PMID 27015285›Full record

ArticleBlood cancer journal2016

Dose-adjusted EPOCH chemotherapy with bortezomib and raltegravir for human T-cell leukemia virus-associated adult T-cell leukemia lymphoma.

L Ratner, D Rauch, H Abel, B Caruso, A Noy, S K Barta, S Parekh, J C Ramos, R Ambinder, A Phillips and 4 more

Abstract readLetter
In one paragraph

Article in Blood cancer journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Revised Adult T-Cell Leukemia-Lymphoma International Consensus Meeting Report.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2019
    Guideline
  2. Review
  3. Review
  4. Review
  5. Review
  6. Article
  7. Review
  8. Article
  9. Review
  10. The Antihelminthic Drug, Mebendazole, Induces Apoptosis in Adult T-Cell Leukemia/Lymphoma Cancer Cells:International journal of hematology-oncology and stem cell research · 2020
    Article
  11. Article
  12. Article
  13. Adult T Cell Leukemia-Lymphoma (ATL): State of the Art.Current hematologic malignancy reports · 2018
    Review
  14. Article
  15. Review
  16. Review
  17. Adult T-Cell Leukemia/Lymphoma.Journal of oncology practice · 2017
    Review
  18. Article
  19. Human T-cell leukemia virus-associated malignancy.Current opinion in virology · 2016
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

L RatnerDivision of Oncology, Department of Medicine, Washington University School of Medicine, St Louis, MO, USA.
D RauchDivision of Oncology, Department of Medicine, Washington University School of Medicine, St Louis, MO, USA.
H AbelDepartment of Genetics, Washington University School of Medicine, St Louis, MO, USA.
B CarusoViral Immunology Section, Neuroimmunology and Neurovirology Division, NINDS, NIH, Bethesda, MD, USA.
A NoyLymphoma Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
S K BartaDivision of Hematology-Oncology, Department of Medicine, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY, USA.
S ParekhDivision of Hematology-Oncology, Department of Medicine, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY, USA.
J C RamosDivision of Hematology-Oncology, Department of Medicine, University of Miami School of Medicine, Miami, FL, USA.
R AmbinderDivision of Hematologic Malignancies, Department of Oncology, Johns Hopkins School of Medicine, Baltimore, MD, USA.
A PhillipsDivision of Hematology-Oncology, Department of Medicine, Columbia University Medical Center, New York, NY, USA.
J HardingDivision of Oncology, Department of Medicine, Washington University School of Medicine, St Louis, MO, USA.
H H BaydounDivision of Oncology, Department of Medicine, Washington University School of Medicine, St Louis, MO, USA.
X ChengDivision of Oncology, Department of Medicine, Washington University School of Medicine, St Louis, MO, USA.
S JacobsonViral Immunology Section, Neuroimmunology and Neurovirology Division, NINDS, NIH, Bethesda, MD, USA.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
Role of Inflammation in Tax-mediated TumorigenesisP01CA100730 · NCI · WASHINGTON UNIVERSITY · PI Malachi Griffith · 2003 to 2026
$44.8M
Targeting the Bone Marrow Microenvironment In Acute Lymphocytic LeukemiaP50CA171963 · NCI · WASHINGTON UNIVERSITY · PI TODD A FEHNIGER · 2013 to 2026
$31.6M
WU-MDACC Inter-Institutional Molecular Imaging CenterP50CA094056 · NCI · WASHINGTON UNIVERSITY · PI KOPAN, RAPHAEL · 2002 to 2016
$26.3M
Translational studies of human viruses and chronic neurologic diseaseZIANS003040 · NINDS · NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE · PI JACOBSON, STEVEN · 2009 to 2025
$10.1M
PROLIFERATIVE EFFECTS OF HTLV1R01CA063417 · NCI · WASHINGTON UNIVERSITY · PI RATNER, LEE · 1995 to 2017
$3.7M
NCI NIH HHS CA10073NCI NIH HHS CA 63417NCI NIH HHS CA94056NCI NIH HHS P01 CA100730NCI NIH HHS P30 CA008748NCI NIH HHS P50 CA094056NCI NIH HHS P50 CA171963NCI NIH HHS R01 CA063417
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Human T-lymphotropic virus 1Antineoplastic Combined Chemotherapy ProtocolsBortezomibCyclophosphamideDoxorubicinEtoposideHTLV-I InfectionsHumansLeukemia-Lymphoma, Adult T-CellPrednisoneRaltegravir PotassiumTreatment OutcomeVincristineBortezomibCyclophosphamideDoxorubicinEtoposidePrednisoneRaltegravir PotassiumVincristine

Identifiers

PMID27015285
PMCPMC4817103

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.