Evidence map›Paper›PMID 27014736›Full record

ArticleData in brief2016

Dataset for phenotypic classification of genetic modifiers of smoothened and Hedgehog.

Suresh Marada, Ashley Truong, Stacey K Ogden

Open access · goldAbstract read
In one paragraph

Article in Data in brief, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 99% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Suresh MaradaDepartment of Cell and Molecular Biology, St. Jude Children׳s Research Hospital, Memphis, TN 38105, USA.
Ashley TruongDepartment of Cell and Molecular Biology, St. Jude Children׳s Research Hospital, Memphis, TN 38105, USA; Rhodes College Summer Plus Program, Rhodes College, Memphis, TN 38112, USA.
Stacey K OgdenDepartment of Cell and Molecular Biology, St. Jude Children׳s Research Hospital, Memphis, TN 38105, USA.
St. Jude Children's Research Hospital · USRhodes College · US

Funding

Viral Vector Technology (VVTSR)P30CA021765 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI CHARLES ROBERTS · 1985 to 2026
$166.9M
Dissecting the Signaling Mechanisms of SmoothenedR01GM101087 · NIGMS · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI OGDEN, STACEY KATHRYN · 2012 to 2016
$1.7M
NCI NIH HHS P30 CA021765NIGMS NIH HHS R01 GM101087
6 · The paper itself

Abstract

This data article includes supporting information for the research article entitled "The Small GTPase Rap1 is a Modulator of Hedgehog Signaling" [1]. Drosophila wing phenotypes induced by expression of a dominant negative Smoothened (Smo) mutant were cataloged into five distinct classes. Class distributions observed following expression of dominant negative Smo in control and sensitized backgrounds were quantified to serve as references for strength of phenotypic modification. Shifts in class distribution of Hedgehog (Hh) wing phenotypes resulting from introduction of loss-of-function alleles of select Ras family G protein genes and the Hh pathway regulators Fused and Suppressor of Fused are shown.

Identifiers

PMID27014736
PMCPMC4792844
OpenAlexW2301487896

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.