ArticleInternational journal of molecular and cellular medicine2015
Adipose-Derived Stem Cells as a Tool for Dental Implant Osseointegration: an Experimental Study in the Dog.
Article in International journal of molecular and cellular medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The trial behind it
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Who cites it
11 citing papers in PubMed, 21 citations in OpenAlex.
- Advanced progress of adipose-derived stem cells-related biomaterials in maxillofacial regeneration.Stem cell research & therapy · 2025Review
- The Use of Mesenchymal Stromal/Stem Cells (MSC) for Periodontal and Peri-implant Regeneration: Scoping Review.Brazilian dental journal · 2024Article
- Assessment of human adipose-derived stem cell on surface-modified silicone implant to reduce capsular contracture formation.Bioengineering & translational medicine · 2022Article
- Advances in Tissue Engineering and Implications for Oral and Maxillofacial Reconstruction.Journal of the California Dental Association · 2021Article
- The effect of bone marrow-derived stem cells associated with platelet-rich plasma on the osseointegration of immediately placed implants.Journal of clinical and experimental dentistry · 2021Article
- An In Vivo Study in Rat Femurs of Bioactive Silicate Coatings on Titanium Dental Implants.Journal of clinical medicine · 2020Article
- Titania Nanofiber Scaffolds with Enhanced Biointegration Activity-Preliminary In Vitro Studies.International journal of molecular sciences · 2019Article
- miR-145-5p suppresses osteogenic differentiation of adipose-derived stem cells by targeting semaphorin 3A.In vitro cellular & developmental biology. Animal · 2019Article
- Exosomes derived from preadipocytes improve osteogenic differentiation, potentially via reduced miR‑223 expression.Molecular medicine reports · 2019Article
- Injectable adipose tissue combined with stem cells for soft-tissue augmentation: A pilot study for dental applications.Journal of dental sciences · 2016Article
- Application of Adipose Tissue Stem Cells in Regenerative Dentistry: A Systematic Review.Journal of International Society of Preventive & Community DentistryReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The biological interaction between the jaw bones and dental implant is fundamental for the long-term success of dental implant placement. Nevertheless, the insufficient bone volume remains a major clinical problem, especially in case of immediate dental implant. Using a canine model, the present study proves the regenerative potential of adipose- derived stem cells (ADSCs) to repair peri-implant bone defects occurring in immediate dental implant placement. In six labradors, all mandibular premolars and the first molars were extracted bilaterally and three months later dental implants were installed with a marginal gap. The marginal defects were filled with hydroxyapatite (HA)-based scaffolds previously seeded with ADSCs. After one month of healing, specimens were prepared for histological and histomorphometric evaluations. Histological analyses of ground sections show that ADSCs significantly increase bone regeneration. Several new vessels, osteoblasts and new bone matrix were detected. By contrast, no inflammatory cells have been revealed. ADSCs could be used to accelerate bone healing in peri- implant defects in case of immediate dental implant placement.
Indexed as
Identifiers
27014644PMC4769597W2179089035What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.