Evidence map›Paper›PMID 27014464›Full record

ArticleNew microbes and new infections2016

Detection of ST772 Panton-Valentine leukocidin-positive methicillin-resistant Staphylococcus aureus (Bengal Bay clone) and ST22 S. aureus isolates with a genetic variant of elastin binding protein in Nepal.

R H Pokhrel, M S Aung, B Thapa, R Chaudhary, S K Mishra, M Kawaguchiya, N Urushibara, N Kobayashi

Open access · goldAbstract read
In one paragraph

Article in New microbes and new infections, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 28 citations in OpenAlex.

  1. Methicillin-ResistantAntibiotics (Basel, Switzerland) · 2025
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  7. Antibiotic resistance profile and molecular characterization of Staphylococcus aureus strains isolated in hospitals in Kabul, Afghanistan.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2021
    Article
  8. Antibiotics (Basel, Switzerland) · 2020
    Article
  9. Article
  10. Article
  11. Article
  12. MRSA Strains in Nepalese Rhesus Macaques (Frontiers in microbiology · 2019
    Article
  13. Multidrug-resistantBioMed research international · 2019
    Article
  14. Article
  15. Emerging multidrug-resistant Bengal Bay clone ST772-MRSA-V in Norway: molecular epidemiology 2004-2014.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

R H PokhrelGenesis Laboratory and Research, Tribhuvan University, Kathmandu, Nepal.
M S AungSapporo Medical University, Sapporo, Japan.
B ThapaGenesis Laboratory and Research, Tribhuvan University, Kathmandu, Nepal.
R ChaudharyNepal Army Institute of Health Sciences, Tribhuvan University, Kathmandu, Nepal.
S K MishraInstitute of Medicine, Tribhuvan University, Kathmandu, Nepal.
M KawaguchiyaSapporo Medical University, Sapporo, Japan.
N UrushibaraSapporo Medical University, Sapporo, Japan.
N KobayashiSapporo Medical University, Sapporo, Japan.
Sapporo Medical University · JPTribhuvan University · NPNepalese Army Institute of Health Services · NP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genetic characteristics were analysed for recent clinical isolates of methicillin-resistant and -susceptible Staphylococcus aureus (MRSA and MSSA respectively) in Kathmandu, Nepal. MRSA isolates harbouring Panton-Valentine leukocidin (PVL) genes were classified into ST1, ST22 and ST88 with SCCmec-IV and ST772 with SCCmec-V (Bengal Bay clone), while PVL-positive MSSA into ST22, ST30 and ST772. ST22 isolates (PVL-positive MRSA and MSSA, PVL-negative MRSA) possessed a variant of elastin binding protein gene (ebpS) with an internal deletion of 180 bp, which was similar to that reported for ST121 S. aureus previously outside Nepal. Phylogenetic analysis indicated that the ebpS variant in ST22 might have occurred independently of ST121 strains. This is the first report of ST772 PVL-positive MRSA in Nepal and detection of the deletion variant of ebpS in ST22 S. aureus.

Indexed as

Bengal Bay cloneelastin binding proteinMRSANepalPanton-Valentine leukocidin (PVL)ST22ST772

Identifiers

PMID27014464
PMCPMC4789347
OpenAlexW2285095178

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.