ArticleFrontiers in microbiology2016
Why Close a Bacterial Genome? The Plasmid of Alteromonas Macleodii HOT1A3 is a Vector for Inter-Specific Transfer of a Flexible Genomic Island.
Article in Frontiers in microbiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Article
- Collaborative metabolic curation of an emerging model marine bacterium, Alteromonas macleodii ATCC 27126.PloS one · 2025Article
- Characterization of membrane vesicles inmicroLife · 2023Article
- Elucidating the genomic history of commercially usedFrontiers in cellular and infection microbiology · 2023Article
- Beyond the ABCs-Discovery of Three New Plasmid Types inMicroorganisms · 2022Article
- Let Me Upgrade You: Impact of Mobile Genetic Elements on Enterococcal Adaptation and Evolution.Journal of bacteriology · 2021Review
- Comparative Genomics ofMicroorganisms · 2020Article
- Article
- Application of magnetic nanoparticles in nucleic acid detection.Journal of nanobiotechnology · 2020Review
- Genomic, metabolic and phenotypic variability shapes ecological differentiation and intraspecies interactions of Alteromonas macleodii.Scientific reports · 2020Article
- Multiple Megaplasmids Confer Extremely High Levels of Metal Tolerance inApplied and environmental microbiology · 2020Article
- The tellurite-reducing bacteriumHeliyon · 2019Article
- Genomic repeats, misassembly and reannotation: a case study with long-read resequencing of Porphyromonas gingivalis reference strains.BMC genomics · 2018Article
- Draft Genome Sequence of Deep-Sea Alteromonas sp. Strain V450 Isolated from the Marine Sponge Leiodermatium sp.Genome announcements · 2017Article
- Networking in microbes: conjugative elements and plasmids in the genus Alteromonas.BMC genomics · 2017Article
- A Metagenomic Approach to Cyanobacterial Genomics.Frontiers in microbiology · 2017Review
- Transcriptional response of Prochlorococcus to co-culture with a marine Alteromonas: differences between strains and the involvement of putative infochemicals.The ISME journal · 2016Article
- How Clonal Is Clonal? Genome Plasticity across Multicellular Segments of a "Candidatus Marithrix sp." Filament from Sulfidic, Briny Seafloor Sediments in the Gulf of Mexico.Frontiers in microbiology · 2016Article
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6 authors.
Funding
Abstract
Genome sequencing is rapidly becoming a staple technique in environmental and clinical microbiology, yet computational challenges still remain, leading to many draft genomes which are typically fragmented into many contigs. We sequenced and completely assembled the genome of a marine heterotrophic bacterium, Alteromonas macleodii HOT1A3, and compared its full genome to several draft genomes obtained using different reference-based and de novo methods. In general, the de novo assemblies clearly outperformed the reference-based or hybrid ones, covering >99% of the genes and representing essentially all of the gene functions. However, only the fully closed genome (∼4.5 Mbp) allowed us to identify the presence of a large, 148 kbp plasmid, pAM1A3. While HOT1A3 belongs to A. macleodii, typically found in surface waters ("surface ecotype"), this plasmid consists of an almost complete flexible genomic island (fGI), containing many genes involved in metal resistance previously identified in the genomes of Alteromonas mediterranea ("deep ecotype"). Indeed, similar to A. mediterranea, A. macleodii HOT1A3 grows at concentrations of zinc, mercury, and copper that are inhibitory for other A. macleodii strains. The presence of a plasmid encoding almost an entire fGI suggests that wholesale genomic exchange between heterotrophic marine bacteria belonging to related but ecologically different populations is not uncommon.
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