ReviewFrontiers in systems neuroscience2016
Cortical-Subcortical Interactions in Depression: From Animal Models to Human Psychopathology.
Review in Frontiers in systems neuroscience, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 78 citations in OpenAlex.
- Individualized Subcortical Functional Brain Organization Is Related to Diagnosis, Symptoms, and Behavior in Major Depressive Disorder.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2026Article
- Article
- Individualized functional brain mapping machine learning prediction of symptom-change resulting from selective kappa-opioid antagonism in an anhedonic sample from a Fast-Fail trial.Journal of mood and anxiety disorders · 2025Article
- Neuromodulation of risk and reward processing during decision making in individuals with general anxiety disorder (GAD).Scientific reports · 2025Article
- Editorial: Neurological insights into communication and synchrony between others: what animal and human group communication can tell us.Frontiers in human neuroscience · 2024Article
- Machine Learning Prediction of Estimated Risk for Bipolar Disorders Using Hippocampal Subfield and Amygdala Nuclei Volumes.Brain sciences · 2023Article
- Performances of whole-brain dynamic and static functional connectivity fingerprinting in machine learning-based classification of major depressive disorder.Frontiers in psychiatry · 2022Article
- Behavioral and Neurochemical Shifts at the Hippocampus and Frontal Cortex Are Associated to Peripheral Inflammation in Balb/c Mice Infected withMicroorganisms · 2021Article
- New Cognitive Neurotechnology Facilitates Studies of Cortical-Subcortical Interactions.Trends in biotechnology · 2020Review
- Altered mesocorticolimbic functional connectivity in chronic low back pain patients at rest and following sad mood induction.Brain imaging and behavior · 2020Article
- Amygdala: Neuroanatomical and Morphophysiological Features in Terms of Neurological and Neurodegenerative Diseases.Brain sciences · 2020Review
- Integrative and Network-Specific Connectivity of the Basal Ganglia and Thalamus Defined in Individuals.Neuron · 2020Article
- Conservative and disruptive modes of adolescent change in human brain functional connectivity.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- MicroRNA-34a Regulates the Depression-like Behavior in Mice by Modulating the Expression of Target Genes in the Dorsal Raphè.Molecular neurobiology · 2020Article
- A tangled web: The reciprocal relationship between depression and educational outcomes in China.Social science research · 2020Article
- The roles of early-life adversity and rumination in neural response to emotional faces amongst anxious and depressed adults.Psychological medicine · 2019Article
- Selective vulnerability of dorsal raphe-medial prefrontal cortex projection neurons to corticosterone-induced hypofunction.The European journal of neuroscience · 2019Article
- Mapping Structure-Function Relationships in the Brain.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2019Review
- Prefrontal Executive Control Rescues Risk for Anxiety Associated with High Threat and Low Reward Brain Function.Cerebral cortex (New York, N.Y. : 1991) · 2019Article
- Abnormal changes in functional connectivity between the amygdala and frontal regions are associated with depression in Alzheimer's disease.Neuroradiology · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Depression is a debilitating disorder causing significant societal and personal suffering. Improvements in identification of major depressive disorder (MDD) and its treatment are essential to reduce its toll. Recent developments in rodent models of MDD and neuroimaging of humans suffering from the disorder provide avenues through which gains can be made towards reducing its burden. In this review, new findings, integrating across rodent models and human imaging are highlighted that have yielded new insights towards a basic understanding of the disorder. In particular, this review focuses on cortical-subcortical interactions underlying the pathophysiology of MDD. In particular, evidence is accruing that dysfunction in prefrontal-subcortical circuits including the amygdala, ventral striatum (VS), hippocampus and dorsal raphe nucleus (DRN) are associated with MDD status.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.