Evidence map›Paper›PMID 27013962›Full record

ReviewFrontiers in neuroscience2016

Laser Nano-Neurosurgery from Gentle Manipulation to Nano-Incision of Neuronal Cells and Scaffolds: An Advanced Neurotechnology Tool.

Alessandro Soloperto, Gemma Palazzolo, Hanako Tsushima, Evelina Chieregatti, Massimo Vassalli, Francesco Difato

Abstract readReview
In one paragraph

Review in Frontiers in neuroscience, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alessandro SolopertoNeuroscience and Brain Technologies Department, Istituto Italiano di Tecnologia Genoa, Italy.
Gemma PalazzoloNeuroscience and Brain Technologies Department, Istituto Italiano di Tecnologia Genoa, Italy.
Hanako TsushimaNeuroscience and Brain Technologies Department, Istituto Italiano di Tecnologia Genoa, Italy.
Evelina ChieregattiNeuroscience and Brain Technologies Department, Istituto Italiano di Tecnologia Genoa, Italy.
Massimo VassalliInstitute of Biophysics, National Research Council of Italy Genoa, Italy.
Francesco DifatoNeuroscience and Brain Technologies Department, Istituto Italiano di Tecnologia Genoa, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Current optical approaches are progressing far beyond the scope of monitoring the structure and function of living matter, and they are becoming widely recognized as extremely precise, minimally-invasive, contact-free handling tools. Laser manipulation of living tissues, single cells, or even single-molecules is becoming a well-established methodology, thus founding the onset of new experimental paradigms and research fields. Indeed, a tightly focused pulsed laser source permits complex tasks such as developing engineered bioscaffolds, applying calibrated forces, transfecting, stimulating, or even ablating single cells with subcellular precision, and operating intracellular surgical protocols at the level of single organelles. In the present review, we report the state of the art of laser manipulation in neuroscience, to inspire future applications of light-assisted tools in nano-neurosurgery.

Indexed as

intracellular surgerylaser dissectionlaser nano-surgeryopto-transfectionphoto-polymerizationphoto-stimulation

Identifiers

PMID27013962
PMCPMC4786546

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.