ArticleIEEE journal of selected topics in quantum electronics : a publication of the IEEE Lasers and Electro-optics Society
The Role of Laser Speckle Imaging in Port-Wine Stain Research: Recent Advances and Opportunities.
Article in IEEE journal of selected topics in quantum electronics : a publication of the IEEE Lasers and Electro-optics Society. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
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Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Treatment Outcome Measurement Instruments for Port Wine Stains: A Systematic Review of Their Measurement Properties.Dermatology (Basel, Switzerland) · 2021Pooled it
- Clinical outcome measures and scoring systems used in prospective studies of port wine stains: A systematic review.PloS one · 2020Pooled it
- Devices and Methods for Dosimetry of Personalized Photodynamic Therapy of Tumors: A Review on Recent Trends.Cancers · 2024Review
- Clinical Observation on the Therapeutic Effect of Port-Wine Stains with Intravenous Injection of Hematoporphyrin Monomethyl Ether (HMME).Clinical, cosmetic and investigational dermatology · 2024Article
- Hemoporfin-Mediated Photodynamic Therapy for Port-Wine Stains on Extremities.Dermatology and therapy · 2023Article
- Adaptive Feature Extraction for Blood Vessel Segmentation and Contrast Recalculation in Laser Speckle Contrast Imaging.Micromachines · 2022Article
- Hemoporfin-Mediated Photodynamic Therapy for Port-Wine Stains: Multivariate Analysis of Clinical Efficacy and Optical Coherence Tomography Appearance.Frontiers in medicine · 2022Article
- Cerebral Blood Flow in Chronic Kidney Disease.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2021Review
- Extraction of the Structural Properties of Skin Tissue via Diffuse Reflectance Spectroscopy: An Inverse Methodology.Sensors (Basel, Switzerland) · 2021Article
- Removing Subcutaneous Microvessels Using Photo-Mediated Ultrasound Therapy.Lasers in surgery and medicine · 2020Article
- In Vivo Assessment of Thermosensitive Liposomes for the Treatment of Port Wine Stains by Antifibrinolytic Site-Specific Pharmaco-Laser Therapy.Pharmaceutics · 2020Article
- Site-specific pharmaco-laser therapy: A novel treatment modality for refractory port wine stains.Journal of clinical and translational research · 2019Review
- Numerical Modeling and Clinical Evaluation of Pulsed Dye Laser and Copper Vapor Laser in Skin Vascular Lesions Treatment.Journal of lasers in medical sciences · 2019Article
- Histologic changes associated with talaporfin sodium-mediated photodynamic therapy in rat skin.Lasers in surgery and medicine · 2017Article
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Authors and funding
10 authors.
Funding
Abstract
Here, we review our current knowledge on the etiology and treatment of port-wine stain (PWS) birthmarks. Current treatment options have significant limitations in terms of efficacy. With the combination of 1) a suitable preclinical microvascular model, 2) laser speckle imaging (LSI) to evaluate blood-flow dynamics, and 3) a longitudinal experimental design, rapid preclinical assessment of new phototherapies can be translated from the lab to the clinic. The combination of photodynamic therapy (PDT) and pulsed-dye laser (PDL) irradiation achieves a synergistic effect that reduces the required radiant exposures of the individual phototherapies to achieve persistent vascular shutdown. PDL combined with anti-angiogenic agents is a promising strategy to achieve persistent vascular shutdown by preventing reformation and reperfusion of photocoagulated blood vessels. Integration of LSI into the clinical workflow may lead to surgical image guidance that maximizes acute photocoagulation, is expected to improve PWS therapeutic outcome. Continued integration of noninvasive optical imaging technologies and biochemical analysis collectively are expected to lead to more robust treatment strategies.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.