Evidence map›Paper›PMID 27013522›Full record

ArticleJournal of the American Medical Informatics Association : JAMIA2016

Preserving temporal relations in clinical data while maintaining privacy.

George Hripcsak, Parsa Mirhaji, Alexander Fh Low, Bradley A Malin

Abstract read
In one paragraph

Article in Journal of the American Medical Informatics Association : JAMIA, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. The Detection of Date Shifting in Real-World Data.Applied clinical informatics · 2023
    Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. The role of ethics in data governance of large neuro-ICT projects.Journal of the American Medical Informatics Association : JAMIA · 2018
    Review
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

George HripcsakDepartment of Biomedical Informatics, Columbia University Medical Center, New York, NY 10032, USA hripcsak@columbia.edu.
Parsa MirhajiMontefiore Medical Center/Albert Einstein College of Medicine, Bronx, New York, NY 10461, USA.
Alexander Fh LowDepartment of Healthcare Policy and Research, Weill Cornell Medical College, New York, NY 10065, USA.
Bradley A MalinDepartment of Biomedical Informatics, School of Medicine, Vanderbilt University, Nashville, TN 37203, USA.

Funding

DISCOVERING AND APPLYING KNOWLEDGE IN CLINICAL DATABASESR01LM006910 · NLM · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI HRIPCSAK, GEORGE M · 2000 to 2023
$10.6M
eMERGE Coordinating Center - Administrative SupplementU01HG006385 · NHGRI · VANDERBILT UNIVERSITY · PI HARRIS, PAUL A. · 2011 to 2014
$5.4M
VGER, the Vanderbilt Genome-Electronic Records ProjectU01HG008672 · NHGRI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI DENNY, JOSHUA C., RODEN, DAN M · 2015 to 2019
$5.1M
Vanderbilt Genome Electronic Records ProjectU01HG006378 · NHGRI · VANDERBILT UNIVERSITY · PI RODEN, DAN M · 2011 to 2014
$4.0M
NHGRI NIH HHS U01 HG006378NHGRI NIH HHS U01 HG006385NHGRI NIH HHS U01 HG008672NLM NIH HHS R01 LM006910
6 · The paper itself

Abstract

objectiveMaintaining patient privacy is a challenge in large-scale observational research. To assist in reducing the risk of identifying study subjects through publicly available data, we introduce a method for obscuring date information for clinical events and patient characteristics.

methodsThe method, which we call Shift and Truncate (SANT), obscures date information to any desired granularity. Shift and Truncate first assigns each patient a random shift value, such that all dates in that patient's record are shifted by that amount. Data are then truncated from the beginning and end of the data set.

resultsThe data set can be proven to not disclose temporal information finer than the chosen granularity. Unlike previous strategies such as a simple shift, it remains robust to frequent - even daily - updates and robust to inferring dates at the beginning and end of date-shifted data sets. Time-of-day may be retained or obscured, depending on the goal and anticipated knowledge of the data recipient.

conclusionsThe method can be useful as a scientific approach for reducing re-identification risk under the Privacy Rule of the Health Insurance Portability and Accountability Act and may contribute to qualification for the Safe Harbor implementation.

Indexed as

ConfidentialityData AnonymizationElectronic Health RecordsHealth Insurance Portability and Accountability ActHumansMethodsObservational Studies as TopicTimeUnited States

Identifiers

PMID27013522
PMCPMC5070517

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.