ArticleJournal of orthopaedic surgery and research2016
Changes in coagulation functions and hemorheological parameters may predict hematoma formation after total knee arthroplasty.
Article in Journal of orthopaedic surgery and research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.
- Indicators and medical tests to identify lower limb swelling causes after total knee arthroplasty: a Delphi study with multidisciplinary experts.Journal of orthopaedic surgery and research · 2023Pooled it
- Effects of ozone combined with articular injection of sodium hyaluronate on patients with knee osteoarthritis and their inflammatory factors and hemorheological indices.African health sciences · 2023Trial
- A prospective cohort study develops and validates a machine learning model for predicting ecchymosis after total knee arthroplasty.Scientific reports · 2026Article
- Risk factors and airway management of postoperative retropharyngeal hematoma following anterior cervical spine surgery: a retrospective study.Journal of orthopaedic surgery and research · 2025Article
- Article
- Delayed Onset Iliopsoas Tendonitis With Intramuscular Hematoma Following Total Hip Arthroplasty.Arthroplasty today · 2024Article
- Personalized delayed anticoagulation therapy alleviates postoperative bleeding in total knee arthroplasty (TKA) patients.Journal of experimental orthopaedics · 2024Article
- Early ambulation after total knee arthroplasty: a retrospective single-center study.Journal of orthopaedic surgery and research · 2024Article
- Article
- Influence of epidural anesthesia and general anesthesia on thromboembolism in patients undergoing total knee arthroplasty.American journal of translational research · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHematoma formation around the knee is commonly seen after total knee arthroplasty (TKA) and may cause patient discomfort and worry regarding the success of the surgery. This study aimed to evaluate the coagulation functions and hemorheological parameters in patients undergoing TKA and investigate their associations with hematoma formation.
methodsThis study prospectively included 146 patients treated for knee osteoarthritis by unilateral TKA between August 2013 and August 2014. Apixaban was administered twice during the 12-24-h period after surgery. Blood coagulation functions were evaluated according to activated partial thromboplastin time (APTT), prothrombin time (PT), thrombin time, and fibrinogen preoperatively and on postoperative days 1, 3, 7, and 14. Hemorheological parameters were also measured. Patients were divided into a hematoma group and a non-hematoma group for comparison.
resultsOn postoperative day 1, the hematoma group showed significantly prolonged APTT and PT and significantly decreased hematocrit relative to baseline values (P < 0.05). The whole blood high shear rate, whole blood low shear rate, plasma viscosity, and hematocrit did not differ significantly between the two groups at baseline or from postoperative days 1-14 in (P > 0.05).
conclusionsProlonged APTT and PT on the first day after TKA as well as decreased hematocrit may indicate an increased risk of hematoma formation. Postoperative use of apixaban may promote the formation of ecchymoses but is not a major contributing factor.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.