SynthesisBiomedical journal2015
The challenges of amblyopia treatment.
Synthesis in Biomedical journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.
- Research hotspots and trends of amblyopia treatment from 2015 to 2025: a bibliometric analysis.Frontiers in neuroscience · 2025Pooled it
- Effects of bifocals on visual acuity in children with Down syndrome: a randomized controlled trial.Acta ophthalmologica · 2019Trial
- Differential Effects of Balanced and Imbalanced Binocular Stimulation on Visual Cortex Responses in Amblyopic Children.Clinical ophthalmology (Auckland, N.Z.) · 2026Article
- Evolving Strategies in Amblyopia Management: From Traditional Therapies to Cutting-Edge Innovations.Cureus · 2025Review
- Colour Vision Deficits in Children with Amblyopia: Impact of Angular Size of Stimuli on Detection.Vision (Basel, Switzerland) · 2025Article
- High Magnesium Promotes the Recovery of Binocular Vision from Amblyopia via TRPM7.Neuroscience bulletin · 2024Article
- Harnessing brain plasticity to improve binocular vision in amblyopia: An evidence-based update.European journal of ophthalmology · 2024Review
- Factors affecting the total occlusion time in eyes with hyperopic anisometropic amblyopia.BMC ophthalmology · 2023Article
- Parents' Awareness, Knowledge, and Perception of Amblyopia in Children: A Study in Jazan Region, Saudi Arabia.Cureus · 2023Article
- Amblyopia and the whole child.Progress in retinal and eye research · 2023Review
- The Effect of Home-Based Dichoptic Therapy on Young Adults with Non-Strabismic Anisometropic Amblyopia on Stereo Acuity.Clinical optometry · 2022Article
- Altered Spontaneous Brain Activity Patterns in Children With Strabismic Amblyopia After Low-Frequency Repetitive Transcranial Magnetic Stimulation: A Resting-State Functional Magnetic Resonance Imaging Study.Frontiers in human neuroscience · 2022Article
- Differences between children with Down syndrome and typically developing children in adaptive behaviour, executive functions and visual acuity.Scientific reports · 2021Article
- Closing the Critical Period Is Required for the Maturation of Binocular Integration in Mouse Primary Visual Cortex.Frontiers in cellular neuroscience · 2021Article
- An update on pharmacological treatment options for amblyopia.International ophthalmology · 2020Review
- Characterization, passive and active treatment in strabismic amblyopia: a narrative review.International journal of ophthalmology · 2020Review
- The treatment of amblyopia: current practice and emerging trends.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2019Review
- Article
- The two faces of invariant natural killer T cells.Biomedical journal · 2015Article
- The awareness of amblyopia among parents in Saudi Arabia.Therapeutic advances in ophthalmologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The treatment of amblyopia, particularly anisometropic (difference in refractive correction) and/or strabismic (turn of one eye) amblyopia has long been a challenge for many clinicians. Achieving optimum outcomes, where the amblyopic eye reaches a visual acuity similar to the fellow eye, is often impossible in many patients. Part of this challenge has resulted from a previous lack of scientific evidence for amblyopia treatment that was highlight by a systematic review by Snowdon et al. in 1998. Since this review, a number of publications have revealed new findings in the treatment of amblyopia. This includes the finding that less intensive occlusion treatments can be successful in treating amblyopia. A relationship between adherence to treatment and visual acuity has also been established and has been shown to be influenced by the use of intervention material. In addition, there is growing evidence of that a period of glasses wearing only can significantly improve visual acuity alone without any other modes of treatment. This review article reports findings since the Snowdon's report.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.