Evidence map›Paper›PMID 27013449›Full record

ReviewBiomedical journal2015

Shared neurocircuitry underlying feeding and drugs of abuse in Drosophila.

Dan Landayan, Fred W Wolf

Abstract readReview
In one paragraph

Review in Biomedical journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. The neuropeptide drosulfakinin enhances choosiness and protects males from the aging effects of social perception.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  3. Article
  4. Article
  5. Sleep Modulates Alcohol Toxicity inInternational journal of molecular sciences · 2022
    Article
  6. Article
  7. Article
  8. Article
  9. Neural Circuits Underlying Behavioral Flexibility: Insights FromFrontiers in behavioral neuroscience · 2021
    Review
  10. Aging and the clock: Perspective from flies to humans.The European journal of neuroscience · 2020
    Review
  11. Article
  12. Review
  13. Insights from intoxicated Drosophila.Alcohol (Fayetteville, N.Y.) · 2019
    Review
  14. Review
  15. A Fly's Eye View of Natural and Drug Reward.Frontiers in physiology · 2018
    Review
  16. Article
  17. Neural plasticity · 2017
    Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Dan LandayanDepartment of Molecular Cell Biology, School of Natural Sciences, University of California, Merced, CA, USA. Electronic address: dlandayan@ucmerced.edu.
Fred W WolfDepartment of Molecular Cell Biology, School of Natural Sciences, University of California, Merced, CA, USA. Electronic address: fwolf@ucmerced.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The neural circuitry and molecules that control the rewarding properties of food and drugs of abuse appear to partially overlap in the mammalian brain. This has raised questions about the extent of the overlap and the precise role of specific circuit elements in reward and in other behaviors associated with feeding regulation and drug responses. The much simpler brain of invertebrates including the fruit fly Drosophila, offers an opportunity to make high-resolution maps of the circuits and molecules that govern behavior. Recent progress in Drosophila has revealed not only some common substrates for the actions of drugs of abuse and for the regulation of feeding, but also a remarkable level of conservation with vertebrates for key neuromodulatory transmitters. We speculate that Drosophila may serve as a model for distinguishing the neural mechanisms underlying normal and pathological motivational states that will be applicable to mammals.

Indexed as

AnimalsDopamineDrosophilaFeeding BehaviorIllicit DrugsModels, AnimalOctopamineTyramineDopamineIllicit DrugsOctopamineTyramineBehaviorDrugsFoodNeural circuitsNeuroscience

Identifiers

PMID27013449
PMCPMC6138758

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.